BDBM50147737 1-(1-Dicyclohexylmethyl-piperidin-4-yl)-1,3-dihydro-indol-2-one::CHEMBL100574

SMILES: O=C1Cc2ccccc2N1C1CCN(CC1)C(C1CCCCC1)C1CCCCC1

InChI Key: InChIKey=PXFVUZDVIRDKOZ-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50147737   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50147737 (1-(1-Dicyclohexylmethyl-piperidin-4-yl)-1,3-dihydr...) Show SMILES O=C1Cc2ccccc2N1C1CCN(CC1)C(C1CCCCC1)C1CCCCC1 Show InChI InChI=1S/C26H38N2O/c29-25-19-22-13-7-8-14-24(22)28(25)23-15-17-27(18-16-23)26(20-9-3-1-4-10-20)21-11-5-2-6-12-21/h7-8,13-14,20-21,23,26H,1-6,9-12,15-19H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	227	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Binding affinity against human Opioid receptor mu 1 on CHO cell membranes was determined by [3H]DAMGO displacement.				J Med Chem 47: 2973-6 (2004) Article DOI: 10.1021/jm034249d BindingDB Entry DOI: 10.7270/Q2KW5FHV
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50147737 (1-(1-Dicyclohexylmethyl-piperidin-4-yl)-1,3-dihydr...) Show SMILES O=C1Cc2ccccc2N1C1CCN(CC1)C(C1CCCCC1)C1CCCCC1 Show InChI InChI=1S/C26H38N2O/c29-25-19-22-13-7-8-14-24(22)28(25)23-15-17-27(18-16-23)26(20-9-3-1-4-10-20)21-11-5-2-6-12-21/h7-8,13-14,20-21,23,26H,1-6,9-12,15-19H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	343	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Binding affinity against human Opioid receptor kappa 1 on CHO cell membranes by [3H]U-69593 displacement.				J Med Chem 47: 2973-6 (2004) Article DOI: 10.1021/jm034249d BindingDB Entry DOI: 10.7270/Q2KW5FHV
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50147737 (1-(1-Dicyclohexylmethyl-piperidin-4-yl)-1,3-dihydr...) Show SMILES O=C1Cc2ccccc2N1C1CCN(CC1)C(C1CCCCC1)C1CCCCC1 Show InChI InChI=1S/C26H38N2O/c29-25-19-22-13-7-8-14-24(22)28(25)23-15-17-27(18-16-23)26(20-9-3-1-4-10-20)21-11-5-2-6-12-21/h7-8,13-14,20-21,23,26H,1-6,9-12,15-19H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Binding affinity against human Nociceptin receptor on CHO cell membranes by [3H]N/OFQ displacement.				J Med Chem 47: 2973-6 (2004) Article DOI: 10.1021/jm034249d BindingDB Entry DOI: 10.7270/Q2KW5FHV
					More data for this Ligand-Target Pair