BDBM50147738 1-[1-(1,2,3,4-Tetrahydro-naphthalen-2-yl)-piperidin-4-yl]-1,3-dihydro-indol-2-one::CHEMBL101676

SMILES: O=C1Cc2ccccc2N1C1CCN(CC1)C1CCc2ccccc2C1

InChI Key: InChIKey=MGIADQYKMHMDKW-UHFFFAOYSA-N

Data: 3 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50147738   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50147738 (1-[1-(1,2,3,4-Tetrahydro-naphthalen-2-yl)-piperidi...) Show SMILES O=C1Cc2ccccc2N1C1CCN(CC1)C1CCc2ccccc2C1 Show InChI InChI=1S/C23H26N2O/c26-23-16-19-7-3-4-8-22(19)25(23)20-11-13-24(14-12-20)21-10-9-17-5-1-2-6-18(17)15-21/h1-8,20-21H,9-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Binding affinity against human Nociceptin receptor on CHO cell membranes by [3H]N/OFQ displacement.				J Med Chem 47: 2973-6 (2004) Article DOI: 10.1021/jm034249d BindingDB Entry DOI: 10.7270/Q2KW5FHV
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50147738 (1-[1-(1,2,3,4-Tetrahydro-naphthalen-2-yl)-piperidi...) Show SMILES O=C1Cc2ccccc2N1C1CCN(CC1)C1CCc2ccccc2C1 Show InChI InChI=1S/C23H26N2O/c26-23-16-19-7-3-4-8-22(19)25(23)20-11-13-24(14-12-20)21-10-9-17-5-1-2-6-18(17)15-21/h1-8,20-21H,9-16H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	39	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Binding affinity against human Opioid receptor mu 1 on CHO cell membranes was determined by [3H]DAMGO displacement.				J Med Chem 47: 2973-6 (2004) Article DOI: 10.1021/jm034249d BindingDB Entry DOI: 10.7270/Q2KW5FHV
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50147738 (1-[1-(1,2,3,4-Tetrahydro-naphthalen-2-yl)-piperidi...) Show SMILES O=C1Cc2ccccc2N1C1CCN(CC1)C1CCc2ccccc2C1 Show InChI InChI=1S/C23H26N2O/c26-23-16-19-7-3-4-8-22(19)25(23)20-11-13-24(14-12-20)21-10-9-17-5-1-2-6-18(17)15-21/h1-8,20-21H,9-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Binding affinity against human Opioid receptor kappa 1 on CHO cell membranes by [3H]U-69593 displacement.				J Med Chem 47: 2973-6 (2004) Article DOI: 10.1021/jm034249d BindingDB Entry DOI: 10.7270/Q2KW5FHV
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50147738 (1-[1-(1,2,3,4-Tetrahydro-naphthalen-2-yl)-piperidi...) Show SMILES O=C1Cc2ccccc2N1C1CCN(CC1)C1CCc2ccccc2C1 Show InChI InChI=1S/C23H26N2O/c26-23-16-19-7-3-4-8-22(19)25(23)20-11-13-24(14-12-20)21-10-9-17-5-1-2-6-18(17)15-21/h1-8,20-21H,9-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	93	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Concentration required for stimulation of [35S]-GTP-gammaS, binding to human Nociceptin receptor in cell membranes				J Med Chem 47: 2973-6 (2004) Article DOI: 10.1021/jm034249d BindingDB Entry DOI: 10.7270/Q2KW5FHV
					More data for this Ligand-Target Pair