BDBM50148025 CHEMBL3763360

SMILES: COc1ccc(\C=C\C(=O)Nc2cc3c(Nc4ccc(F)c(Cl)c4)ncnc3cc2O[C@H]2CCOC2)cc1

InChI Key: InChIKey=PKVCAQKGXZUIDA-ZTJJKMQJSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50148025   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50148025 (CHEMBL3763360) Show SMILES COc1ccc(\C=C\C(=O)Nc2cc3c(Nc4ccc(F)c(Cl)c4)ncnc3cc2O[C@H]2CCOC2)cc1 |r| Show InChI InChI=1S/C28H24ClFN4O4/c1-36-19-6-2-17(3-7-19)4-9-27(35)34-25-13-21-24(14-26(25)38-20-10-11-37-15-20)31-16-32-28(21)33-18-5-8-23(30)22(29)12-18/h2-9,12-14,16,20H,10-11,15H2,1H3,(H,34,35)(H,31,32,33)/b9-4+/t20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	886	n/a	n/a	n/a	n/a	n/a	n/a
Jiangxi Science& Technology Normal University Curated by ChEMBL					Assay Description Inhibition of VEGFR2 (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by addition of substrate by mobility s...				Bioorg Med Chem 24: 1495-503 (2016) BindingDB Entry DOI: 10.7270/Q2KS6TCZ
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50148025 (CHEMBL3763360) Show SMILES COc1ccc(\C=C\C(=O)Nc2cc3c(Nc4ccc(F)c(Cl)c4)ncnc3cc2O[C@H]2CCOC2)cc1 |r| Show InChI InChI=1S/C28H24ClFN4O4/c1-36-19-6-2-17(3-7-19)4-9-27(35)34-25-13-21-24(14-26(25)38-20-10-11-37-15-20)31-16-32-28(21)33-18-5-8-23(30)22(29)12-18/h2-9,12-14,16,20H,10-11,15H2,1H3,(H,34,35)(H,31,32,33)/b9-4+/t20-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9.10	n/a	n/a	n/a	n/a	n/a	n/a
Jiangxi Science& Technology Normal University Curated by ChEMBL					Assay Description Inhibition of EGFR (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by addition of substrate by mobility shi...				Bioorg Med Chem 24: 1495-503 (2016) BindingDB Entry DOI: 10.7270/Q2KS6TCZ
					More data for this Ligand-Target Pair