BDBM50148026 CHEMBL3763790

SMILES: COc1ccc(\C=C\C(=O)Nc2cc3c(Nc4ccc(F)c(Cl)c4)ncnc3cc2O[C@H]2CCOC2)c(OC)c1OC

InChI Key: InChIKey=OELHXJQUNXVIPN-SQUITACLSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50148026   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50148026 (CHEMBL3763790) Show SMILES COc1ccc(\C=C\C(=O)Nc2cc3c(Nc4ccc(F)c(Cl)c4)ncnc3cc2O[C@H]2CCOC2)c(OC)c1OC |r| Show InChI InChI=1S/C30H28ClFN4O6/c1-38-25-8-4-17(28(39-2)29(25)40-3)5-9-27(37)36-24-13-20-23(14-26(24)42-19-10-11-41-15-19)33-16-34-30(20)35-18-6-7-22(32)21(31)12-18/h4-9,12-14,16,19H,10-11,15H2,1-3H3,(H,36,37)(H,33,34,35)/b9-5+/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	478	n/a	n/a	n/a	n/a	n/a	n/a
Jiangxi Science& Technology Normal University Curated by ChEMBL					Assay Description Inhibition of VEGFR2 (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by addition of substrate by mobility s...				Bioorg Med Chem 24: 1495-503 (2016) BindingDB Entry DOI: 10.7270/Q2KS6TCZ
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50148026 (CHEMBL3763790) Show SMILES COc1ccc(\C=C\C(=O)Nc2cc3c(Nc4ccc(F)c(Cl)c4)ncnc3cc2O[C@H]2CCOC2)c(OC)c1OC |r| Show InChI InChI=1S/C30H28ClFN4O6/c1-38-25-8-4-17(28(39-2)29(25)40-3)5-9-27(37)36-24-13-20-23(14-26(24)42-19-10-11-41-15-19)33-16-34-30(20)35-18-6-7-22(32)21(31)12-18/h4-9,12-14,16,19H,10-11,15H2,1-3H3,(H,36,37)(H,33,34,35)/b9-5+/t19-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
Jiangxi Science& Technology Normal University Curated by ChEMBL					Assay Description Inhibition of EGFR (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by addition of substrate by mobility shi...				Bioorg Med Chem 24: 1495-503 (2016) BindingDB Entry DOI: 10.7270/Q2KS6TCZ
					More data for this Ligand-Target Pair