BDBM50148250 CHEMBL3765222
SMILES: [H][C@@]12CC=CC[C@]1([H])C(=NN(C1CCCCCC1)C2=O)c1ccc(OC)c(OCc2cccc(OC)c2OC)c1
InChI Key: InChIKey=BLITYKVFEYLYIE-LOSJGSFVSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Class I phosphodiesterase B1 (TbrPDEB1) (Trypanosoma brucei) | BDBM50148250 (CHEMBL3765222) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 79 | n/a | n/a | n/a | n/a | n/a | n/a |
Mercachem Curated by ChEMBL | Assay Description Inhibition of recombinant Trypanosoma brucei PDEB1 using [3H]-cAMP as substrate after 15 mins by scintillation proximity assay | Bioorg Med Chem 24: 1573-81 (2016) BindingDB Entry DOI: 10.7270/Q22V2J07 | |||||||||||
More data for this Ligand-Target Pair |