null

SMILES: N[C@@H](Cc1ccc(O)cc1)C(=O)N1CC(F)(F)C[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CC(F)(F)C[C@@H]1C(N)=O

InChI Key: InChIKey=OXGIXGFYQQZLSO-KJJMTIBFSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50148259   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50148259 (CHEMBL3765406) Show SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N1CC(F)(F)C[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CC(F)(F)C[C@@H]1C(N)=O |r| Show InChI InChI=1S/C28H31F4N5O5/c29-27(30)12-21(23(34)39)36(14-27)26(42)20(11-16-4-2-1-3-5-16)35-24(40)22-13-28(31,32)15-37(22)25(41)19(33)10-17-6-8-18(38)9-7-17/h1-9,19-22,38H,10-15,33H2,(H2,34,39)(H,35,40)/t19-,20-,21+,22-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.370	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Lodz Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from MOR in Wistar rat brain homogenate by scintillation counting analysis				Bioorg Med Chem 24: 1582-8 (2016) Article DOI: 10.1016/j.bmc.2016.02.034 BindingDB Entry DOI: 10.7270/Q2Z321H7
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50148259 (CHEMBL3765406) Show SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N1CC(F)(F)C[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CC(F)(F)C[C@@H]1C(N)=O |r| Show InChI InChI=1S/C28H31F4N5O5/c29-27(30)12-21(23(34)39)36(14-27)26(42)20(11-16-4-2-1-3-5-16)35-24(40)22-13-28(31,32)15-37(22)25(41)19(33)10-17-6-8-18(38)9-7-17/h1-9,19-22,38H,10-15,33H2,(H2,34,39)(H,35,40)/t19-,20-,21+,22-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Lodz Curated by ChEMBL					Assay Description Displacement of [3H][Ile5,6]deltorphin-2 from DOR in Wistar rat brain homogenate by scintillation counting analysis				Bioorg Med Chem 24: 1582-8 (2016) Article DOI: 10.1016/j.bmc.2016.02.034 BindingDB Entry DOI: 10.7270/Q2Z321H7
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50148259 (CHEMBL3765406) Show SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N1CC(F)(F)C[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CC(F)(F)C[C@@H]1C(N)=O |r| Show InChI InChI=1S/C28H31F4N5O5/c29-27(30)12-21(23(34)39)36(14-27)26(42)20(11-16-4-2-1-3-5-16)35-24(40)22-13-28(31,32)15-37(22)25(41)19(33)10-17-6-8-18(38)9-7-17/h1-9,19-22,38H,10-15,33H2,(H2,34,39)(H,35,40)/t19-,20-,21+,22-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	813	n/a	n/a	n/a	n/a
Medical University of Lodz Curated by ChEMBL					Assay Description Agonist activity at human recombinant KOR expressed in CHO cells by calcium mobilization assay				Bioorg Med Chem 24: 1582-8 (2016) Article DOI: 10.1016/j.bmc.2016.02.034 BindingDB Entry DOI: 10.7270/Q2Z321H7
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50148259 (CHEMBL3765406) Show SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N1CC(F)(F)C[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CC(F)(F)C[C@@H]1C(N)=O |r| Show InChI InChI=1S/C28H31F4N5O5/c29-27(30)12-21(23(34)39)36(14-27)26(42)20(11-16-4-2-1-3-5-16)35-24(40)22-13-28(31,32)15-37(22)25(41)19(33)10-17-6-8-18(38)9-7-17/h1-9,19-22,38H,10-15,33H2,(H2,34,39)(H,35,40)/t19-,20-,21+,22-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	4.70	n/a	n/a	n/a	n/a
Medical University of Lodz Curated by ChEMBL					Assay Description Agonist activity at human recombinant MOR expressed in CHO cells by calcium mobilization assay				Bioorg Med Chem 24: 1582-8 (2016) Article DOI: 10.1016/j.bmc.2016.02.034 BindingDB Entry DOI: 10.7270/Q2Z321H7
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50148259 (CHEMBL3765406) Show SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N1CC(F)(F)C[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CC(F)(F)C[C@@H]1C(N)=O |r| Show InChI InChI=1S/C28H31F4N5O5/c29-27(30)12-21(23(34)39)36(14-27)26(42)20(11-16-4-2-1-3-5-16)35-24(40)22-13-28(31,32)15-37(22)25(41)19(33)10-17-6-8-18(38)9-7-17/h1-9,19-22,38H,10-15,33H2,(H2,34,39)(H,35,40)/t19-,20-,21+,22-/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	386	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Lodz Curated by ChEMBL					Assay Description Displacement of [3H]nor-BNI from KOR in Dunkin Hartley guinea pig brain homogenate by scintillation counting analysis				Bioorg Med Chem 24: 1582-8 (2016) Article DOI: 10.1016/j.bmc.2016.02.034 BindingDB Entry DOI: 10.7270/Q2Z321H7
					More data for this Ligand-Target Pair