BDBM50148411 (3-Hexadecylamino-propyl)-phosphonic acid::CHEMBL115738
SMILES: CCCCCCCCCCCCCCCCNCCCP(O)(O)=O
InChI Key: InChIKey=YHDAWQLKEJHZMN-UHFFFAOYSA-N
Data: 5 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sphingosine 1-phosphate receptor 2 (Homo sapiens (Human)) | BDBM50148411 ((3-Hexadecylamino-propyl)-phosphonic acid | CHEMBL...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Binding affinity to human sphingosine 1-phosphate receptor 5 expressed in CHO cells was determined by using [33P]-S1P as radioligand | Bioorg Med Chem Lett 14: 3495-9 (2004) Article DOI: 10.1016/j.bmcl.2004.04.069 BindingDB Entry DOI: 10.7270/Q2SF2WRM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine 1-phosphate receptor 4 (Homo sapiens (Human)) | BDBM50148411 ((3-Hexadecylamino-propyl)-phosphonic acid | CHEMBL...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Binding affinity to human sphingosine 1-phosphate receptor 4 expressed in CHO cells was determined by using [33P]-S1P as radioligand | Bioorg Med Chem Lett 14: 3495-9 (2004) Article DOI: 10.1016/j.bmcl.2004.04.069 BindingDB Entry DOI: 10.7270/Q2SF2WRM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine 1-phosphate receptor 2 (Homo sapiens (Human)) | BDBM50148411 ((3-Hexadecylamino-propyl)-phosphonic acid | CHEMBL...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 740 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Binding affinity to human sphingosine 1-phosphate receptor 2 expressed in CHO cells was determined by using [33P]-S1P as radioligand | Bioorg Med Chem Lett 14: 3495-9 (2004) Article DOI: 10.1016/j.bmcl.2004.04.069 BindingDB Entry DOI: 10.7270/Q2SF2WRM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human)) | BDBM50148411 ((3-Hexadecylamino-propyl)-phosphonic acid | CHEMBL...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Binding affinity to human sphingosine 1-phosphate receptor 3 expressed in CHO cells was determined by using [33P]-S1P as radioligand | Bioorg Med Chem Lett 14: 3495-9 (2004) Article DOI: 10.1016/j.bmcl.2004.04.069 BindingDB Entry DOI: 10.7270/Q2SF2WRM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human)) | BDBM50148411 ((3-Hexadecylamino-propyl)-phosphonic acid | CHEMBL...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Binding affinity to human Sphingosine 1-phosphate receptor 1 expressed in CHO cells was determined by using [33P]-S1P as radioligand | Bioorg Med Chem Lett 14: 3495-9 (2004) Article DOI: 10.1016/j.bmcl.2004.04.069 BindingDB Entry DOI: 10.7270/Q2SF2WRM | |||||||||||
More data for this Ligand-Target Pair |