BDBM50148534 2-[(1-Amino-2-cyclohexyl-ethyl)-hydroxy-phosphinoylmethyl]-3-(4-fluoro-phenyl)-acrylic acid::CHEMBL119055::CHEMBL119723

SMILES: OC(=O)C(Cc1ccc(F)cc1)CP(O)(=O)C(=N)CC1CCCCC1

InChI Key: InChIKey=QMNSNNIDXYDZAS-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50148534   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Renal dipeptidase (Homo sapiens (Human))	BDBM50148534 (2-[(1-Amino-2-cyclohexyl-ethyl)-hydroxy-phosphinoy...) Show SMILES OC(=O)C(Cc1ccc(F)cc1)CP(O)(=O)C(=N)CC1CCCCC1 Show InChI InChI=1S/C18H25FNO4P/c19-16-8-6-14(7-9-16)10-15(18(21)22)12-25(23,24)17(20)11-13-4-2-1-3-5-13/h6-9,13,15,20H,1-5,10-12H2,(H,21,22)(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Curated by ChEMBL					Assay Description Concentration required to inhibit renal dipeptidase (RDP) by 50% in crude lysates prepared from human colon cancer				Bioorg Med Chem Lett 14: 3531-3 (2004) Article DOI: 10.1016/j.bmcl.2004.04.057 BindingDB Entry DOI: 10.7270/Q2GX4B1C
					More data for this Ligand-Target Pair
Dehydropeptidase-I (DHP-1) (Homo sapiens (Human))	BDBM50148534 (2-[(1-Amino-2-cyclohexyl-ethyl)-hydroxy-phosphinoy...) Show SMILES OC(=O)C(Cc1ccc(F)cc1)CP(O)(=O)C(=N)CC1CCCCC1 Show InChI InChI=1S/C18H25FNO4P/c19-16-8-6-14(7-9-16)10-15(18(21)22)12-25(23,24)17(20)11-13-4-2-1-3-5-13/h6-9,13,15,20H,1-5,10-12H2,(H,21,22)(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Curated by ChEMBL					Assay Description Concentration required to inhibit renal dipeptidase (RDP) by 50% in crude lysates prepared from human colon cancer				Bioorg Med Chem Lett 14: 3531-3 (2004) Article DOI: 10.1016/j.bmcl.2004.04.057 BindingDB Entry DOI: 10.7270/Q2GX4B1C
					More data for this Ligand-Target Pair