Found 19 hits for monomerid = 50148690 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Epidermal growth factor receptor and ErbB2 (HER1 and HER2)
(Homo sapiens (Human)) | BDBM50148690
(4-[5-(2-Cyclohexylamino-pyridin-4-yl)-4-(4-fluoro-...)Show SMILES OC1(CCNCC1)c1nc(c(o1)-c1ccnc(NC2CCCCC2)c1)-c1ccc(F)cc1 Show InChI InChI=1S/C25H29FN4O2/c26-19-8-6-17(7-9-19)22-23(32-24(30-22)25(31)11-14-27-15-12-25)18-10-13-28-21(16-18)29-20-4-2-1-3-5-20/h6-10,13,16,20,27,31H,1-5,11-12,14-15H2,(H,28,29) | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of human epidermal growth factor receptor |
Bioorg Med Chem Lett 14: 3595-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.03.106 BindingDB Entry DOI: 10.7270/Q2V69J2C |
More data for this Ligand-Target Pair | |
Insulin-like growth factor I receptor
(Homo sapiens (Human)) | BDBM50148690
(4-[5-(2-Cyclohexylamino-pyridin-4-yl)-4-(4-fluoro-...)Show SMILES OC1(CCNCC1)c1nc(c(o1)-c1ccnc(NC2CCCCC2)c1)-c1ccc(F)cc1 Show InChI InChI=1S/C25H29FN4O2/c26-19-8-6-17(7-9-19)22-23(32-24(30-22)25(31)11-14-27-15-12-25)18-10-13-28-21(16-18)29-20-4-2-1-3-5-20/h6-10,13,16,20,27,31H,1-5,11-12,14-15H2,(H,28,29) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of human insulin-like growth factor I receptor |
Bioorg Med Chem Lett 14: 3595-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.03.106 BindingDB Entry DOI: 10.7270/Q2V69J2C |
More data for this Ligand-Target Pair | |
Cyclooxygenase-1 (COX-1)
(Homo sapiens (Human)) | BDBM50148690
(4-[5-(2-Cyclohexylamino-pyridin-4-yl)-4-(4-fluoro-...)Show SMILES OC1(CCNCC1)c1nc(c(o1)-c1ccnc(NC2CCCCC2)c1)-c1ccc(F)cc1 Show InChI InChI=1S/C25H29FN4O2/c26-19-8-6-17(7-9-19)22-23(32-24(30-22)25(31)11-14-27-15-12-25)18-10-13-28-21(16-18)29-20-4-2-1-3-5-20/h6-10,13,16,20,27,31H,1-5,11-12,14-15H2,(H,28,29) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >8.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of human prostaglandin G/H synthase 1, COX-1 |
Bioorg Med Chem Lett 14: 3595-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.03.106 BindingDB Entry DOI: 10.7270/Q2V69J2C |
More data for this Ligand-Target Pair | |
Cytochrome P450 2D6
(Homo sapiens (Human)) | BDBM50148690
(4-[5-(2-Cyclohexylamino-pyridin-4-yl)-4-(4-fluoro-...)Show SMILES OC1(CCNCC1)c1nc(c(o1)-c1ccnc(NC2CCCCC2)c1)-c1ccc(F)cc1 Show InChI InChI=1S/C25H29FN4O2/c26-19-8-6-17(7-9-19)22-23(32-24(30-22)25(31)11-14-27-15-12-25)18-10-13-28-21(16-18)29-20-4-2-1-3-5-20/h6-10,13,16,20,27,31H,1-5,11-12,14-15H2,(H,28,29) | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of human cytochrome P450 2D6 |
Bioorg Med Chem Lett 14: 3595-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.03.106 BindingDB Entry DOI: 10.7270/Q2V69J2C |
More data for this Ligand-Target Pair | |
RAF proto-oncogene serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM50148690
(4-[5-(2-Cyclohexylamino-pyridin-4-yl)-4-(4-fluoro-...)Show SMILES OC1(CCNCC1)c1nc(c(o1)-c1ccnc(NC2CCCCC2)c1)-c1ccc(F)cc1 Show InChI InChI=1S/C25H29FN4O2/c26-19-8-6-17(7-9-19)22-23(32-24(30-22)25(31)11-14-27-15-12-25)18-10-13-28-21(16-18)29-20-4-2-1-3-5-20/h6-10,13,16,20,27,31H,1-5,11-12,14-15H2,(H,28,29) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 8.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of human RAF proto-oncogene serine/threonine-protein kinase |
Bioorg Med Chem Lett 14: 3595-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.03.106 BindingDB Entry DOI: 10.7270/Q2V69J2C |
More data for this Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50148690
(4-[5-(2-Cyclohexylamino-pyridin-4-yl)-4-(4-fluoro-...)Show SMILES OC1(CCNCC1)c1nc(c(o1)-c1ccnc(NC2CCCCC2)c1)-c1ccc(F)cc1 Show InChI InChI=1S/C25H29FN4O2/c26-19-8-6-17(7-9-19)22-23(32-24(30-22)25(31)11-14-27-15-12-25)18-10-13-28-21(16-18)29-20-4-2-1-3-5-20/h6-10,13,16,20,27,31H,1-5,11-12,14-15H2,(H,28,29) | PDB MMDB
KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of human Met proto-oncogene tyrosine kinase |
Bioorg Med Chem Lett 14: 3595-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.03.106 BindingDB Entry DOI: 10.7270/Q2V69J2C |
More data for this Ligand-Target Pair | |
Cytochrome P450 1A
(Homo sapiens (Human)) | BDBM50148690
(4-[5-(2-Cyclohexylamino-pyridin-4-yl)-4-(4-fluoro-...)Show SMILES OC1(CCNCC1)c1nc(c(o1)-c1ccnc(NC2CCCCC2)c1)-c1ccc(F)cc1 Show InChI InChI=1S/C25H29FN4O2/c26-19-8-6-17(7-9-19)22-23(32-24(30-22)25(31)11-14-27-15-12-25)18-10-13-28-21(16-18)29-20-4-2-1-3-5-20/h6-10,13,16,20,27,31H,1-5,11-12,14-15H2,(H,28,29) | PDB MMDB
Reactome pathway KEGG
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of human cytochrome P450 1A2 |
Bioorg Med Chem Lett 14: 3595-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.03.106 BindingDB Entry DOI: 10.7270/Q2V69J2C |
More data for this Ligand-Target Pair | |
Cytochrome P450 3A4
(Homo sapiens (Human)) | BDBM50148690
(4-[5-(2-Cyclohexylamino-pyridin-4-yl)-4-(4-fluoro-...)Show SMILES OC1(CCNCC1)c1nc(c(o1)-c1ccnc(NC2CCCCC2)c1)-c1ccc(F)cc1 Show InChI InChI=1S/C25H29FN4O2/c26-19-8-6-17(7-9-19)22-23(32-24(30-22)25(31)11-14-27-15-12-25)18-10-13-28-21(16-18)29-20-4-2-1-3-5-20/h6-10,13,16,20,27,31H,1-5,11-12,14-15H2,(H,28,29) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of human cytochrome P450 3A4 |
Bioorg Med Chem Lett 14: 3595-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.03.106 BindingDB Entry DOI: 10.7270/Q2V69J2C |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase ABL1
(Homo sapiens (Human)) | BDBM50148690
(4-[5-(2-Cyclohexylamino-pyridin-4-yl)-4-(4-fluoro-...)Show SMILES OC1(CCNCC1)c1nc(c(o1)-c1ccnc(NC2CCCCC2)c1)-c1ccc(F)cc1 Show InChI InChI=1S/C25H29FN4O2/c26-19-8-6-17(7-9-19)22-23(32-24(30-22)25(31)11-14-27-15-12-25)18-10-13-28-21(16-18)29-20-4-2-1-3-5-20/h6-10,13,16,20,27,31H,1-5,11-12,14-15H2,(H,28,29) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of human c-Abl |
Bioorg Med Chem Lett 14: 3595-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.03.106 BindingDB Entry DOI: 10.7270/Q2V69J2C |
More data for this Ligand-Target Pair | |
Cytochrome P450 2C9
(Homo sapiens (Human)) | BDBM50148690
(4-[5-(2-Cyclohexylamino-pyridin-4-yl)-4-(4-fluoro-...)Show SMILES OC1(CCNCC1)c1nc(c(o1)-c1ccnc(NC2CCCCC2)c1)-c1ccc(F)cc1 Show InChI InChI=1S/C25H29FN4O2/c26-19-8-6-17(7-9-19)22-23(32-24(30-22)25(31)11-14-27-15-12-25)18-10-13-28-21(16-18)29-20-4-2-1-3-5-20/h6-10,13,16,20,27,31H,1-5,11-12,14-15H2,(H,28,29) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of human cytochrome P450 2C9 |
Bioorg Med Chem Lett 14: 3595-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.03.106 BindingDB Entry DOI: 10.7270/Q2V69J2C |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 8
(Homo sapiens (Human)) | BDBM50148690
(4-[5-(2-Cyclohexylamino-pyridin-4-yl)-4-(4-fluoro-...)Show SMILES OC1(CCNCC1)c1nc(c(o1)-c1ccnc(NC2CCCCC2)c1)-c1ccc(F)cc1 Show InChI InChI=1S/C25H29FN4O2/c26-19-8-6-17(7-9-19)22-23(32-24(30-22)25(31)11-14-27-15-12-25)18-10-13-28-21(16-18)29-20-4-2-1-3-5-20/h6-10,13,16,20,27,31H,1-5,11-12,14-15H2,(H,28,29) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of human c-Jun N-terminal kinase 1 |
Bioorg Med Chem Lett 14: 3595-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.03.106 BindingDB Entry DOI: 10.7270/Q2V69J2C |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50148690
(4-[5-(2-Cyclohexylamino-pyridin-4-yl)-4-(4-fluoro-...)Show SMILES OC1(CCNCC1)c1nc(c(o1)-c1ccnc(NC2CCCCC2)c1)-c1ccc(F)cc1 Show InChI InChI=1S/C25H29FN4O2/c26-19-8-6-17(7-9-19)22-23(32-24(30-22)25(31)11-14-27-15-12-25)18-10-13-28-21(16-18)29-20-4-2-1-3-5-20/h6-10,13,16,20,27,31H,1-5,11-12,14-15H2,(H,28,29) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of human vascular endothelial growth factor receptor 2 |
Bioorg Med Chem Lett 14: 3595-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.03.106 BindingDB Entry DOI: 10.7270/Q2V69J2C |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50148690
(4-[5-(2-Cyclohexylamino-pyridin-4-yl)-4-(4-fluoro-...)Show SMILES OC1(CCNCC1)c1nc(c(o1)-c1ccnc(NC2CCCCC2)c1)-c1ccc(F)cc1 Show InChI InChI=1S/C25H29FN4O2/c26-19-8-6-17(7-9-19)22-23(32-24(30-22)25(31)11-14-27-15-12-25)18-10-13-28-21(16-18)29-20-4-2-1-3-5-20/h6-10,13,16,20,27,31H,1-5,11-12,14-15H2,(H,28,29) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of human c-Src |
Bioorg Med Chem Lett 14: 3595-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.03.106 BindingDB Entry DOI: 10.7270/Q2V69J2C |
More data for this Ligand-Target Pair | |
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human)) | BDBM50148690
(4-[5-(2-Cyclohexylamino-pyridin-4-yl)-4-(4-fluoro-...)Show SMILES OC1(CCNCC1)c1nc(c(o1)-c1ccnc(NC2CCCCC2)c1)-c1ccc(F)cc1 Show InChI InChI=1S/C25H29FN4O2/c26-19-8-6-17(7-9-19)22-23(32-24(30-22)25(31)11-14-27-15-12-25)18-10-13-28-21(16-18)29-20-4-2-1-3-5-20/h6-10,13,16,20,27,31H,1-5,11-12,14-15H2,(H,28,29) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of human c-Kit kinase |
Bioorg Med Chem Lett 14: 3595-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.03.106 BindingDB Entry DOI: 10.7270/Q2V69J2C |
More data for this Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50148690
(4-[5-(2-Cyclohexylamino-pyridin-4-yl)-4-(4-fluoro-...)Show SMILES OC1(CCNCC1)c1nc(c(o1)-c1ccnc(NC2CCCCC2)c1)-c1ccc(F)cc1 Show InChI InChI=1S/C25H29FN4O2/c26-19-8-6-17(7-9-19)22-23(32-24(30-22)25(31)11-14-27-15-12-25)18-10-13-28-21(16-18)29-20-4-2-1-3-5-20/h6-10,13,16,20,27,31H,1-5,11-12,14-15H2,(H,28,29) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of human epidermal growth factor receptor |
Bioorg Med Chem Lett 14: 3595-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.03.106 BindingDB Entry DOI: 10.7270/Q2V69J2C |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 9
(Homo sapiens (Human)) | BDBM50148690
(4-[5-(2-Cyclohexylamino-pyridin-4-yl)-4-(4-fluoro-...)Show SMILES OC1(CCNCC1)c1nc(c(o1)-c1ccnc(NC2CCCCC2)c1)-c1ccc(F)cc1 Show InChI InChI=1S/C25H29FN4O2/c26-19-8-6-17(7-9-19)22-23(32-24(30-22)25(31)11-14-27-15-12-25)18-10-13-28-21(16-18)29-20-4-2-1-3-5-20/h6-10,13,16,20,27,31H,1-5,11-12,14-15H2,(H,28,29) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of human c-Jun N-terminal kinase 2 |
Bioorg Med Chem Lett 14: 3595-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.03.106 BindingDB Entry DOI: 10.7270/Q2V69J2C |
More data for this Ligand-Target Pair | |
MAP kinase p38
(Mus musculus (mouse)) | BDBM50148690
(4-[5-(2-Cyclohexylamino-pyridin-4-yl)-4-(4-fluoro-...)Show SMILES OC1(CCNCC1)c1nc(c(o1)-c1ccnc(NC2CCCCC2)c1)-c1ccc(F)cc1 Show InChI InChI=1S/C25H29FN4O2/c26-19-8-6-17(7-9-19)22-23(32-24(30-22)25(31)11-14-27-15-12-25)18-10-13-28-21(16-18)29-20-4-2-1-3-5-20/h6-10,13,16,20,27,31H,1-5,11-12,14-15H2,(H,28,29) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of murine phosphorylated His-Mitogen-activated protein kinase p38 alpha. |
Bioorg Med Chem Lett 14: 3595-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.03.106 BindingDB Entry DOI: 10.7270/Q2V69J2C |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 1
(Homo sapiens (Human)) | BDBM50148690
(4-[5-(2-Cyclohexylamino-pyridin-4-yl)-4-(4-fluoro-...)Show SMILES OC1(CCNCC1)c1nc(c(o1)-c1ccnc(NC2CCCCC2)c1)-c1ccc(F)cc1 Show InChI InChI=1S/C25H29FN4O2/c26-19-8-6-17(7-9-19)22-23(32-24(30-22)25(31)11-14-27-15-12-25)18-10-13-28-21(16-18)29-20-4-2-1-3-5-20/h6-10,13,16,20,27,31H,1-5,11-12,14-15H2,(H,28,29) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of human cyclin-dependent kinase 1 |
Bioorg Med Chem Lett 14: 3595-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.03.106 BindingDB Entry DOI: 10.7270/Q2V69J2C |
More data for this Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50148690
(4-[5-(2-Cyclohexylamino-pyridin-4-yl)-4-(4-fluoro-...)Show SMILES OC1(CCNCC1)c1nc(c(o1)-c1ccnc(NC2CCCCC2)c1)-c1ccc(F)cc1 Show InChI InChI=1S/C25H29FN4O2/c26-19-8-6-17(7-9-19)22-23(32-24(30-22)25(31)11-14-27-15-12-25)18-10-13-28-21(16-18)29-20-4-2-1-3-5-20/h6-10,13,16,20,27,31H,1-5,11-12,14-15H2,(H,28,29) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of human Epidermal growth factor receptor, HER-1 |
Bioorg Med Chem Lett 14: 3595-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.03.106 BindingDB Entry DOI: 10.7270/Q2V69J2C |
More data for this Ligand-Target Pair | |