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SMILES: C[C@H](Nc1cc(ccn1)-c1nc([nH]c1-c1ccc(F)cc1)C1(O)CCN(C)CC1)c1ccccc1

InChI Key: InChIKey=NIHRDFVTTPUXSZ-IBGZPJMESA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50148693   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 14


(Mus musculus (mouse))		BDBM50148693
PNG
(4-{4-(4-Fluoro-phenyl)-5-[2-((S)-1-phenyl-ethylami...)
Show SMILES C[C@H](Nc1cc(ccn1)-c1nc([nH]c1-c1ccc(F)cc1)C1(O)CCN(C)CC1)c1ccccc1
Show InChI InChI=1S/C28H30FN5O/c1-19(20-6-4-3-5-7-20)31-24-18-22(12-15-30-24)26-25(21-8-10-23(29)11-9-21)32-27(33-26)28(35)13-16-34(2)17-14-28/h3-12,15,18-19,35H,13-14,16-17H2,1-2H3,(H,30,31)(H,32,33)/t19-/m0/s1
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n/an/a 7n/an/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Inhibition of murine phosphorylated His-Mitogen-activated protein kinase p38 alpha.

Bioorg Med Chem Lett 14: 3595-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.03.106
BindingDB Entry DOI: 10.7270/Q2V69J2C
More data for this
Ligand-Target Pair