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SMILES: C[C@H](Nc1nccc(n1)-c1oc(nc1-c1ccc(F)cc1)C1(O)CCN(C)CC1)c1ccccc1

InChI Key: InChIKey=NFQBSQZNMWBYAC-SFHVURJKSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50148697   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 14


(Mus musculus (mouse))		BDBM50148697
PNG
(4-{4-(4-Fluoro-phenyl)-5-[2-((S)-1-phenyl-ethylami...)
Show SMILES C[C@H](Nc1nccc(n1)-c1oc(nc1-c1ccc(F)cc1)C1(O)CCN(C)CC1)c1ccccc1
Show InChI InChI=1S/C27H28FN5O2/c1-18(19-6-4-3-5-7-19)30-26-29-15-12-22(31-26)24-23(20-8-10-21(28)11-9-20)32-25(35-24)27(34)13-16-33(2)17-14-27/h3-12,15,18,34H,13-14,16-17H2,1-2H3,(H,29,30,31)/t18-/m0/s1
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n/an/a 11n/an/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Inhibition of murine phosphorylated His-Mitogen-activated protein kinase p38 alpha.

Bioorg Med Chem Lett 14: 3595-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.03.106
BindingDB Entry DOI: 10.7270/Q2V69J2C
More data for this
Ligand-Target Pair