BindingDB logo
myBDB logout

null

SMILES: ONC(=O)\C=C\c1cccc(c1)C(C(=O)Nc1ccccc1)C(=O)Nc1ccccc1

InChI Key: InChIKey=SQGNVWSNUGLNRK-CCEZHUSRSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50148757   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone deacetylase 1


(Homo sapiens (Human))		BDBM50148757
PNG
(2-[3-(2-Hydroxycarbamoyl-vinyl)-phenyl]-N,N'-diphe...)
Show SMILES ONC(=O)\C=C\c1cccc(c1)C(C(=O)Nc1ccccc1)C(=O)Nc1ccccc1
Show InChI InChI=1S/C24H21N3O4/c28-21(27-31)15-14-17-8-7-9-18(16-17)22(23(29)25-19-10-3-1-4-11-19)24(30)26-20-12-5-2-6-13-20/h1-16,22,31H,(H,25,29)(H,26,30)(H,27,28)/b15-14+
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents
Article
PubMed
n/an/a 1n/an/an/an/an/an/a



University of Notre Dame

Curated by ChEMBL


Assay Description
Inhibitory activity against human Histone deacetylase 1

J Med Chem 47: 3409-17 (2004)


Article DOI: 10.1021/jm0498497
BindingDB Entry DOI: 10.7270/Q2G16085
More data for this
Ligand-Target Pair