BDBM50148762 CHEMBL3142917::[1-[2',5'-Bis-O-(tert-butyldimethylsilyl)-beta-D-ribofuranosyl]-3-N-[3-[[[(methoxycarbonyl)hydroxyphosphonyl]oxy]-propyl]thymine]-3''-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide); Sodium ion

SMILES: [Na+].COC(=O)P([O-])(=O)OCCCn1c(=O)c(C)cn([C@@H]2O[C@H](CO[Si](C)(C)C(C)(C)C)[C@@]3(OS(=O)(=O)C=C3N)[C@H]2O[Si](C)(C)C(C)(C)C)c1=O

InChI Key: InChIKey=VAWQHGBUNNNRMH-UHFFFAOYSA-M

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50148762   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50148762 (CHEMBL3142917 | [1-[2',5'-Bis-O-(tert-butyldimethy...) Show SMILES [Na+].COC(=O)P([O-])(=O)OCCCn1c(=O)c(C)cn([C@@H]2O[C@H](CO[Si](C)(C)C(C)(C)C)[C@@]3(OS(=O)(=O)C=C3N)[C@H]2O[Si](C)(C)C(C)(C)C)c1=O |r,c:35| Show InChI InChI=1S/C29H52N3O13PSSi2/c1-19-16-32(25(34)31(23(19)33)14-13-15-41-46(36,37)26(35)40-8)24-22(44-49(11,12)28(5,6)7)29(20(30)18-47(38,39)45-29)21(43-24)17-42-48(9,10)27(2,3)4/h16,18,21-22,24H,13-15,17,30H2,1-12H3,(H,36,37)/p-1	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Química Médica (C.S.I.C.) Curated by ChEMBL					Assay Description Inhibitory concentration against wild type HIV-1 reverse transcriptase (RT) using poly rC.dG as the template or primer				J Med Chem 47: 3418-26 (2004) Article DOI: 10.1021/jm031045o BindingDB Entry DOI: 10.7270/Q2B857KW
					More data for this Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50148762 (CHEMBL3142917 | [1-[2',5'-Bis-O-(tert-butyldimethy...) Show SMILES [Na+].COC(=O)P([O-])(=O)OCCCn1c(=O)c(C)cn([C@@H]2O[C@H](CO[Si](C)(C)C(C)(C)C)[C@@]3(OS(=O)(=O)C=C3N)[C@H]2O[Si](C)(C)C(C)(C)C)c1=O |r,c:35| Show InChI InChI=1S/C29H52N3O13PSSi2/c1-19-16-32(25(34)31(23(19)33)14-13-15-41-46(36,37)26(35)40-8)24-22(44-49(11,12)28(5,6)7)29(20(30)18-47(38,39)45-29)21(43-24)17-42-48(9,10)27(2,3)4/h16,18,21-22,24H,13-15,17,30H2,1-12H3,(H,36,37)/p-1	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.94E+5	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Química Médica (C.S.I.C.) Curated by ChEMBL					Assay Description Inhibitory concentration against wild type HIV-1/138Lys reverse transcriptase (RT) using [3H]dGTP as a radioligand				J Med Chem 47: 3418-26 (2004) Article DOI: 10.1021/jm031045o BindingDB Entry DOI: 10.7270/Q2B857KW
					More data for this Ligand-Target Pair