BDBM50148898 CHEMBL333903::[3-(4-Chloro-phenyl)-2,5-dimethyl-3H-pyrazolo[1,5-a]pyrimidin-7-yl]-dipropyl-amine

SMILES: CCCN(CCC)c1cc(C)nc2c(c(C)nn12)-c1ccc(Cl)cc1

InChI Key: InChIKey=DOPVGJROKFQOTD-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50148898   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50148898 (CHEMBL333903 | [3-(4-Chloro-phenyl)-2,5-dimethyl-3...) Show SMILES CCCN(CCC)c1cc(C)nc2c(c(C)nn12)-c1ccc(Cl)cc1 Show InChI InChI=1S/C20H25ClN4/c1-5-11-24(12-6-2)18-13-14(3)22-20-19(15(4)23-25(18)20)16-7-9-17(21)10-8-16/h7-10,13H,5-6,11-12H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity to the cloned human corticotropin releasing factor receptor 1				Bioorg Med Chem Lett 14: 3669-73 (2004) Article DOI: 10.1016/j.bmcl.2004.05.019 BindingDB Entry DOI: 10.7270/Q2T72GWP
					More data for this Ligand-Target Pair