BDBM50149084 2-[2-(5-Chloro-thiophen-2-yl)-1H-benzoimidazol-5-yl]-N-(3,4,5,6-tetrahydro-2H-[1,4']bipyridinyl-4-ylmethyl)-acetamide::CHEMBL126208

SMILES: Clc1ccc(s1)-c1nc2ccc(CC(=O)NCC3CCN(CC3)c3ccncc3)cc2[nH]1

InChI Key: InChIKey=XIDQDPPMVSCHMG-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50149084   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Trypsin (Homo sapiens (Human))	BDBM50149084 (2-[2-(5-Chloro-thiophen-2-yl)-1H-benzoimidazol-5-y...) Show SMILES Clc1ccc(s1)-c1nc2ccc(CC(=O)NCC3CCN(CC3)c3ccncc3)cc2[nH]1 Show InChI InChI=1S/C24H24ClN5OS/c25-22-4-3-21(32-22)24-28-19-2-1-17(13-20(19)29-24)14-23(31)27-15-16-7-11-30(12-8-16)18-5-9-26-10-6-18/h1-6,9-10,13,16H,7-8,11-12,14-15H2,(H,27,31)(H,28,29)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck KGaA Curated by ChEMBL					Assay Description Binding affinity against human trypsin				Bioorg Med Chem Lett 14: 3763-9 (2004) Article DOI: 10.1016/j.bmcl.2004.04.097 BindingDB Entry DOI: 10.7270/Q25H7FQS
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50149084 (2-[2-(5-Chloro-thiophen-2-yl)-1H-benzoimidazol-5-y...) Show SMILES Clc1ccc(s1)-c1nc2ccc(CC(=O)NCC3CCN(CC3)c3ccncc3)cc2[nH]1 Show InChI InChI=1S/C24H24ClN5OS/c25-22-4-3-21(32-22)24-28-19-2-1-17(13-20(19)29-24)14-23(31)27-15-16-7-11-30(12-8-16)18-5-9-26-10-6-18/h1-6,9-10,13,16H,7-8,11-12,14-15H2,(H,27,31)(H,28,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck KGaA Curated by ChEMBL					Assay Description Binding affinity against human thrombin.				Bioorg Med Chem Lett 14: 3763-9 (2004) Article DOI: 10.1016/j.bmcl.2004.04.097 BindingDB Entry DOI: 10.7270/Q25H7FQS
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50149084 (2-[2-(5-Chloro-thiophen-2-yl)-1H-benzoimidazol-5-y...) Show SMILES Clc1ccc(s1)-c1nc2ccc(CC(=O)NCC3CCN(CC3)c3ccncc3)cc2[nH]1 Show InChI InChI=1S/C24H24ClN5OS/c25-22-4-3-21(32-22)24-28-19-2-1-17(13-20(19)29-24)14-23(31)27-15-16-7-11-30(12-8-16)18-5-9-26-10-6-18/h1-6,9-10,13,16H,7-8,11-12,14-15H2,(H,27,31)(H,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Merck KGaA Curated by ChEMBL					Assay Description Binding affinity of the compoumd to human coagulation factor Xa				Bioorg Med Chem Lett 14: 3763-9 (2004) Article DOI: 10.1016/j.bmcl.2004.04.097 BindingDB Entry DOI: 10.7270/Q25H7FQS
					More data for this Ligand-Target Pair