BDBM50149244 CHEMBL3771118
SMILES: COc1ncc(C)cc1CC[C@@](O)(CC(O)=O)C(O)=O
InChI Key: InChIKey=FGYMJXFSHBLHLW-CYBMUJFWSA-N
Data: 12 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Solute carrier family 13 member 5 (Homo sapiens (Human)) | BDBM50149244 (CHEMBL3771118) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 510 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of NaCT (unknown origin) expressed in HEK293 cells assessed as inhibition of [14C]citrate uptake by microbeta plate reader analysis | J Med Chem 59: 1165-75 (2016) BindingDB Entry DOI: 10.7270/Q2ZW1NRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 13 member 5 (Homo sapiens (Human)) | BDBM50149244 (CHEMBL3771118) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 740 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of NaCT in human hepatocytes assessed as [14C]-citrate uptake after 30 mins by scintillation counting method | J Med Chem 59: 1165-75 (2016) BindingDB Entry DOI: 10.7270/Q2ZW1NRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 13 member 2 (Homo sapiens (Human)) | BDBM50149244 (CHEMBL3771118) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.32E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of NaDC1 (unknown origin) expressed in HEK293 cells assessed as inhibition of [14C]citrate uptake by microbeta plate reader analysis | J Med Chem 59: 1165-75 (2016) BindingDB Entry DOI: 10.7270/Q2ZW1NRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 13 member 3 (Homo sapiens (Human)) | BDBM50149244 (CHEMBL3771118) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.41E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of NaDC3 (unknown origin) expressed in HEK293 cells assessed as inhibition of [14C]citrate uptake by microbeta plate reader analysis | J Med Chem 59: 1165-75 (2016) BindingDB Entry DOI: 10.7270/Q2ZW1NRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 13 member 5 (Homo sapiens (Human)) | BDBM50149244 (CHEMBL3771118) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 501 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of NaCT (unknown origin) expressed in HEK293 cells assessed as inhibition of [14C]citrate uptake by microbeta plate reader analysis | J Med Chem 59: 1165-75 (2016) BindingDB Entry DOI: 10.7270/Q2ZW1NRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 13 member 5 (Rattus norvegicus) | BDBM50149244 (CHEMBL3771118) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of NaCT in rat hepatocytes assessed as [14C]-citrate uptake after 30 mins by scintillation counting method | J Med Chem 59: 1165-75 (2016) BindingDB Entry DOI: 10.7270/Q2ZW1NRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 13 member 2 (Homo sapiens (Human)) | BDBM50149244 (CHEMBL3771118) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of NaDC1 (unknown origin) expressed in HEK293 cells assessed as inhibition of [14C]citrate uptake by microbeta plate reader analysis | J Med Chem 59: 1165-75 (2016) BindingDB Entry DOI: 10.7270/Q2ZW1NRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 13 member 3 (Homo sapiens (Human)) | BDBM50149244 (CHEMBL3771118) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of NaDC3 (unknown origin) expressed in HEK293 cells assessed as inhibition of [14C]citrate uptake by microbeta plate reader analysis | J Med Chem 59: 1165-75 (2016) BindingDB Entry DOI: 10.7270/Q2ZW1NRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 13 member 5 (Mus musculus) | BDBM50149244 (CHEMBL3771118) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 214 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of NaCT in mouse hepatocytes assessed as [14C]-citrate uptake after 30 mins by scintillation counting method | J Med Chem 59: 1165-75 (2016) BindingDB Entry DOI: 10.7270/Q2ZW1NRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 13 member 5 (Rattus norvegicus) | BDBM50149244 (CHEMBL3771118) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 126 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of NaCT in rat hepatocytes assessed as [14C]-citrate uptake after 30 mins by scintillation counting method | J Med Chem 59: 1165-75 (2016) BindingDB Entry DOI: 10.7270/Q2ZW1NRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 13 member 5 (Mus musculus) | BDBM50149244 (CHEMBL3771118) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of NaCT in mouse hepatocytes assessed as [14C]-citrate uptake after 30 mins by scintillation counting method | J Med Chem 59: 1165-75 (2016) BindingDB Entry DOI: 10.7270/Q2ZW1NRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 13 member 5 (Homo sapiens (Human)) | BDBM50149244 (CHEMBL3771118) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 794 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of NaCT in human hepatocytes assessed as [14C]-citrate uptake after 30 mins by scintillation counting method | J Med Chem 59: 1165-75 (2016) BindingDB Entry DOI: 10.7270/Q2ZW1NRC | |||||||||||
More data for this Ligand-Target Pair |