BDBM50149347 1-Cyclopropylmethyl-1H-imidazole::1-Subsituted 1H-imidazole, 6::CHEMBL116766
SMILES: C(C1CC1)n1ccnc1
InChI Key: InChIKey=BSRRKSSFRABLLB-UHFFFAOYSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cytochrome P450 2A6 (Homo sapiens (Human)) | BDBM50149347 (1-Cyclopropylmethyl-1H-imidazole | 1-Subsituted 1H...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.40E+4 | n/a | n/a | n/a | n/a | 7.6 | 37 |
University of Basel | Assay Description Inhibition assay using cytochrome P450 enzyme CYP2A6 and CYP2A13. | Chembiochem 10: 1562-7 (2009) Article DOI: 10.1002/cbic.200800712 BindingDB Entry DOI: 10.7270/Q2R78CR9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450-cam (Pseudomonas putida) | BDBM50149347 (1-Cyclopropylmethyl-1H-imidazole | 1-Subsituted 1H...) | PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California Curated by ChEMBL | Assay Description Inhibition of wild type cytochrome P450cam expressed in Escherichia coli | J Med Chem 47: 3572-9 (2004) Article DOI: 10.1021/jm030608t BindingDB Entry DOI: 10.7270/Q20R9NVP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 2A13 (CYP2A13) (Homo sapiens (Human)) | BDBM50149347 (1-Cyclopropylmethyl-1H-imidazole | 1-Subsituted 1H...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.48E+5 | n/a | n/a | n/a | n/a | 7.6 | 37 |
University of Basel | Assay Description Inhibition assay using cytochrome P450 enzyme CYP2A6 and CYP2A13. | Chembiochem 10: 1562-7 (2009) Article DOI: 10.1002/cbic.200800712 BindingDB Entry DOI: 10.7270/Q2R78CR9 | |||||||||||
More data for this Ligand-Target Pair |