BDBM50149654 Butyl-[3-(3-chloro-5-trifluoromethyl-pyridin-2-yl)-2,5-dimethyl-pyrazolo[1,5-a]pyrimidin-7-yl]-propyl-amine::CHEMBL181536

SMILES: CCCCN(CCC)c1cc(C)nc2c(c(C)nn12)-c1ncc(cc1Cl)C(F)(F)F

InChI Key: InChIKey=DSSYQJMKOFDETQ-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50149654   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50149654 (Butyl-[3-(3-chloro-5-trifluoromethyl-pyridin-2-yl)...) Show SMILES CCCCN(CCC)c1cc(C)nc2c(c(C)nn12)-c1ncc(cc1Cl)C(F)(F)F |(8.11,-1.27,;7.55,.16,;6.01,.37,;5.42,1.79,;3.89,1.99,;3.3,3.4,;4.24,4.64,;3.65,6.07,;2.95,.76,;3.54,-.66,;2.6,-1.88,;3.18,-3.3,;1.07,-1.67,;.5,-.24,;-.95,.25,;-.93,1.8,;-2.14,2.73,;.57,2.23,;1.45,.95,;-2.35,-.4,;-2.35,-1.97,;-3.68,-2.74,;-5.01,-1.97,;-5.01,-.43,;-3.68,.37,;-3.71,1.91,;-6.35,-2.74,;-7.58,-3.43,;-7.86,-2.16,;-6.63,-4.33,)| Show InChI InChI=1S/C21H25ClF3N5/c1-5-7-9-29(8-6-2)17-10-13(3)27-20-18(14(4)28-30(17)20)19-16(22)11-15(12-26-19)21(23,24)25/h10-12H,5-9H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity for recombinant human CRF1 receptor				Bioorg Med Chem Lett 14: 3943-7 (2004) Article DOI: 10.1016/j.bmcl.2004.05.056 BindingDB Entry DOI: 10.7270/Q2KK9B7F
					More data for this Ligand-Target Pair