BDBM50149914 CHEMBL3770030

SMILES: O=c1[nH]c(Oc2cnn(Cc3cccnc3)c2)nc2cnccc12

InChI Key: InChIKey=QDESLFWSLVXYOU-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50149914   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM50149914 (CHEMBL3770030) Show SMILES O=c1[nH]c(Oc2cnn(Cc3cccnc3)c2)nc2cnccc12 Show InChI InChI=1S/C28H24BrN5O5S/c29-20-14-15-25(31-17-20)34-26(35)16-23(28(37)32-21-6-2-1-3-7-21)33-27(36)19-12-10-18(11-13-19)22-8-4-5-9-24(22)40(30,38)39/h1-15,17,23H,16H2,(H,32,37)(H,33,36)(H2,30,38,39)(H,31,34,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.26E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Inhibition of N-terminal his-tagged full-length human KDM4C transfected in U2OS cells assessed as inhibition of H3K9Me3 demethylation for 24 hrs				J Med Chem 59: 1370-87 (2016) BindingDB Entry DOI: 10.7270/Q26D5VV2
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM50149914 (CHEMBL3770030) Show SMILES O=c1[nH]c(Oc2cnn(Cc3cccnc3)c2)nc2cnccc12 Show InChI InChI=1S/C28H24BrN5O5S/c29-20-14-15-25(31-17-20)34-26(35)16-23(28(37)32-21-6-2-1-3-7-21)33-27(36)19-12-10-18(11-13-19)22-8-4-5-9-24(22)40(30,38)39/h1-15,17,23H,16H2,(H,32,37)(H,33,36)(H2,30,38,39)(H,31,34,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	631	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Inhibition of N-terminal his-tagged human KDM4C expressed in Escherichia coli BL21(DE3) using trimethylated peptide substrate by RFMS assay				J Med Chem 59: 1370-87 (2016) BindingDB Entry DOI: 10.7270/Q26D5VV2
					More data for this Ligand-Target Pair