BDBM50149915 CHEMBL3769669

SMILES: COc1cccc(Cn2cc(Oc3nc4cnccc4c(=O)[nH]3)cn2)c1

InChI Key: InChIKey=SNAJTJZQHOWXAL-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50149915   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM50149915 (CHEMBL3769669) Show SMILES COc1cccc(Cn2cc(Oc3nc4cnccc4c(=O)[nH]3)cn2)c1 Show InChI InChI=1S/C27H23BrN6O5S/c28-19-7-10-24(31-16-19)34-25(35)15-22(33-26(36)18-11-13-30-14-12-18)27(37)32-20-8-5-17(6-9-20)21-3-1-2-4-23(21)40(29,38)39/h1-14,16,22H,15H2,(H,32,37)(H,33,36)(H2,29,38,39)(H,31,34,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.31E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Inhibition of N-terminal his-tagged full-length human KDM4C transfected in U2OS cells assessed as inhibition of H3K9Me3 demethylation for 24 hrs				J Med Chem 59: 1370-87 (2016) BindingDB Entry DOI: 10.7270/Q26D5VV2
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM50149915 (CHEMBL3769669) Show SMILES COc1cccc(Cn2cc(Oc3nc4cnccc4c(=O)[nH]3)cn2)c1 Show InChI InChI=1S/C27H23BrN6O5S/c28-19-7-10-24(31-16-19)34-25(35)15-22(33-26(36)18-11-13-30-14-12-18)27(37)32-20-8-5-17(6-9-20)21-3-1-2-4-23(21)40(29,38)39/h1-14,16,22H,15H2,(H,32,37)(H,33,36)(H2,29,38,39)(H,31,34,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	631	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Inhibition of N-terminal his-tagged human KDM4C expressed in Escherichia coli BL21(DE3) using trimethylated peptide substrate by RFMS assay				J Med Chem 59: 1370-87 (2016) BindingDB Entry DOI: 10.7270/Q26D5VV2
					More data for this Ligand-Target Pair