BDBM50149922 CHEMBL3769647

SMILES: Cn1cc(Oc2nc3cnccc3c(=O)[nH]2)cn1

InChI Key: InChIKey=UTQOZNPCPGRGHM-LJQANCHMSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50149922   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM50149922 (CHEMBL3769647) Show SMILES Cn1cc(Oc2nc3cnccc3c(=O)[nH]2)cn1 Show InChI InChI=1S/C24H29BrN6O3/c1-30(2)22(26)16-6-8-17(9-7-16)23(33)28-19(24(34)31-12-4-3-5-13-31)14-21(32)29-20-11-10-18(25)15-27-20/h6-11,15,19,26H,3-5,12-14H2,1-2H3,(H,28,33)(H,27,29,32)/t19-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.94E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Inhibition of N-terminal his-tagged full-length human KDM4C transfected in U2OS cells assessed as inhibition of H3K9Me3 demethylation for 24 hrs				J Med Chem 59: 1370-87 (2016) BindingDB Entry DOI: 10.7270/Q26D5VV2
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM50149922 (CHEMBL3769647) Show SMILES Cn1cc(Oc2nc3cnccc3c(=O)[nH]2)cn1 Show InChI InChI=1S/C24H29BrN6O3/c1-30(2)22(26)16-6-8-17(9-7-16)23(33)28-19(24(34)31-12-4-3-5-13-31)14-21(32)29-20-11-10-18(25)15-27-20/h6-11,15,19,26H,3-5,12-14H2,1-2H3,(H,28,33)(H,27,29,32)/t19-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	398	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Inhibition of N-terminal his-tagged human KDM4C expressed in Escherichia coli BL21(DE3) using trimethylated peptide substrate by RFMS assay				J Med Chem 59: 1370-87 (2016) BindingDB Entry DOI: 10.7270/Q26D5VV2
					More data for this Ligand-Target Pair