BDBM50150056 CHEMBL3770864

SMILES: COc1ccc(CN(c2nc(ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)C(F)(F)F)S(=O)(=O)c2ccc(F)cc2)cc1

InChI Key: InChIKey=PYNPATCHJQZVPM-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50150056   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50150056 (CHEMBL3770864) Show SMILES COc1ccc(CN(c2nc(ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)C(F)(F)F)S(=O)(=O)c2ccc(F)cc2)cc1 Show InChI InChI=1S/C31H29F5N4O6S2/c1-19(21-6-14-27(26(33)16-21)39-47(3,42)43)30(41)37-17-22-7-15-28(31(34,35)36)38-29(22)40(18-20-4-10-24(46-2)11-5-20)48(44,45)25-12-8-23(32)9-13-25/h4-16,19,39H,17-18H2,1-3H3,(H,37,41)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Displacement of [3H]RTX from human TRPV1 expressed in CHO cells after 60 mins by scintillation counting analysis				Bioorg Med Chem 24: 1231-40 (2016) BindingDB Entry DOI: 10.7270/Q25D8TP7
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50150056 (CHEMBL3770864) Show SMILES COc1ccc(CN(c2nc(ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)C(F)(F)F)S(=O)(=O)c2ccc(F)cc2)cc1 Show InChI InChI=1S/C31H29F5N4O6S2/c1-19(21-6-14-27(26(33)16-21)39-47(3,42)43)30(41)37-17-22-7-15-28(31(34,35)36)38-29(22)40(18-20-4-10-24(46-2)11-5-20)48(44,45)25-12-8-23(32)9-13-25/h4-16,19,39H,17-18H2,1-3H3,(H,37,41)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of capsaicin-induced (45)Ca2+ uptake after 5 mins by liquid scintill...				Bioorg Med Chem 24: 1231-40 (2016) BindingDB Entry DOI: 10.7270/Q25D8TP7
					More data for this Ligand-Target Pair