BDBM50150088 CHEMBL124818::[4-(1H-Indol-3-yl)-butyl]-[2-(2-methoxy-phenoxy)-ethyl]-amine

SMILES: COc1ccccc1OCCNCCCCc1c[nH]c2ccccc12

InChI Key: InChIKey=SOVXXZPVUNBMAR-UHFFFAOYSA-N

Data: 2 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50150088   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50150088 (CHEMBL124818 | [4-(1H-Indol-3-yl)-butyl]-[2-(2-met...) Show SMILES COc1ccccc1OCCNCCCCc1c[nH]c2ccccc12 Show InChI InChI=1S/C21H26N2O2/c1-24-20-11-4-5-12-21(20)25-15-14-22-13-7-6-8-17-16-23-19-10-3-2-9-18(17)19/h2-5,9-12,16,22-23H,6-8,13-15H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	7.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Binding affinity against human 5-hydroxytryptamine 1A receptor in CHO cells labeled with [3H]-8-OH-DPAT radioligand				J Med Chem 47: 3823-42 (2004) Article DOI: 10.1021/jm0304010 BindingDB Entry DOI: 10.7270/Q2S46RDW
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50150088 (CHEMBL124818 | [4-(1H-Indol-3-yl)-butyl]-[2-(2-met...) Show SMILES COc1ccccc1OCCNCCCCc1c[nH]c2ccccc12 Show InChI InChI=1S/C21H26N2O2/c1-24-20-11-4-5-12-21(20)25-15-14-22-13-7-6-8-17-16-23-19-10-3-2-9-18(17)19/h2-5,9-12,16,22-23H,6-8,13-15H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	31.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Binding affinity against serotonin transporter in rat cortical tissues using radioligand [3H]-paroxetine				J Med Chem 47: 3823-42 (2004) Article DOI: 10.1021/jm0304010 BindingDB Entry DOI: 10.7270/Q2S46RDW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50150088 (CHEMBL124818 | [4-(1H-Indol-3-yl)-butyl]-[2-(2-met...) Show SMILES COc1ccccc1OCCNCCCCc1c[nH]c2ccccc12 Show InChI InChI=1S/C21H26N2O2/c1-24-20-11-4-5-12-21(20)25-15-14-22-13-7-6-8-17-16-23-19-10-3-2-9-18(17)19/h2-5,9-12,16,22-23H,6-8,13-15H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	44	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Effective concentration against binding of radioligand [35]GTPgammaS in CHO cells expressing human 5-hydroxytryptamine 1A receptor				J Med Chem 47: 3823-42 (2004) Article DOI: 10.1021/jm0304010 BindingDB Entry DOI: 10.7270/Q2S46RDW
					More data for this Ligand-Target Pair