BDBM50150097 CHEMBL339810::[2-(5-Fluoro-2,3-dihydro-benzofuran-7-yloxy)-ethyl]-[3-(5-fluoro-1H-indol-3-yl)-propyl]-amine

SMILES: Fc1cc2CCOc2c(OCCNCCCc2c[nH]c3ccc(F)cc23)c1

InChI Key: InChIKey=NTASJIHWLYXQFW-UHFFFAOYSA-N

Data: 2 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50150097   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50150097 (CHEMBL339810 | [2-(5-Fluoro-2,3-dihydro-benzofuran...) Show SMILES Fc1cc2CCOc2c(OCCNCCCc2c[nH]c3ccc(F)cc23)c1 Show InChI InChI=1S/C21H22F2N2O2/c22-16-3-4-19-18(11-16)15(13-25-19)2-1-6-24-7-9-26-20-12-17(23)10-14-5-8-27-21(14)20/h3-4,10-13,24-25H,1-2,5-9H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Binding affinity against serotonin transporter in rat cortical tissues using radioligand [3H]-paroxetine				J Med Chem 47: 3823-42 (2004) Article DOI: 10.1021/jm0304010 BindingDB Entry DOI: 10.7270/Q2S46RDW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50150097 (CHEMBL339810 | [2-(5-Fluoro-2,3-dihydro-benzofuran...) Show SMILES Fc1cc2CCOc2c(OCCNCCCc2c[nH]c3ccc(F)cc23)c1 Show InChI InChI=1S/C21H22F2N2O2/c22-16-3-4-19-18(11-16)15(13-25-19)2-1-6-24-7-9-26-20-12-17(23)10-14-5-8-27-21(14)20/h3-4,10-13,24-25H,1-2,5-9H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	17.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Binding affinity against human 5-hydroxytryptamine 1A receptor in CHO cells labeled with [3H]-8-OH-DPAT radioligand				J Med Chem 47: 3823-42 (2004) Article DOI: 10.1021/jm0304010 BindingDB Entry DOI: 10.7270/Q2S46RDW
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50150097 (CHEMBL339810 | [2-(5-Fluoro-2,3-dihydro-benzofuran...) Show SMILES Fc1cc2CCOc2c(OCCNCCCc2c[nH]c3ccc(F)cc23)c1 Show InChI InChI=1S/C21H22F2N2O2/c22-16-3-4-19-18(11-16)15(13-25-19)2-1-6-24-7-9-26-20-12-17(23)10-14-5-8-27-21(14)20/h3-4,10-13,24-25H,1-2,5-9H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	61.5	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition concentration against [3H]-5-HT uptake by human serotonin transporter in JAR cells				J Med Chem 47: 3823-42 (2004) Article DOI: 10.1021/jm0304010 BindingDB Entry DOI: 10.7270/Q2S46RDW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50150097 (CHEMBL339810 | [2-(5-Fluoro-2,3-dihydro-benzofuran...) Show SMILES Fc1cc2CCOc2c(OCCNCCCc2c[nH]c3ccc(F)cc23)c1 Show InChI InChI=1S/C21H22F2N2O2/c22-16-3-4-19-18(11-16)15(13-25-19)2-1-6-24-7-9-26-20-12-17(23)10-14-5-8-27-21(14)20/h3-4,10-13,24-25H,1-2,5-9H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	445	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition concentration against 5-hydroxytryptamine 1A receptor using cAMP as radioligand in CHO cells				J Med Chem 47: 3823-42 (2004) Article DOI: 10.1021/jm0304010 BindingDB Entry DOI: 10.7270/Q2S46RDW
					More data for this Ligand-Target Pair