BDBM50150134 CHEMBL3771211

SMILES: C[C@H]1CN=C2N1c1nn(Cc3ccc(cc3)-c3ccccc3)c(Nc3ccccc3)c1C(=O)N2C

InChI Key: InChIKey=VFCNKEMDWFEMIT-IBGZPJMESA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50150134   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human))	BDBM50150134 (CHEMBL3771211) Show SMILES C[C@H]1CN=C2N1c1nn(Cc3ccc(cc3)-c3ccccc3)c(Nc3ccccc3)c1C(=O)N2C |r,c:3| Show InChI InChI=1S/C28H26N6O/c1-19-17-29-28-32(2)27(35)24-25(30-23-11-7-4-8-12-23)33(31-26(24)34(19)28)18-20-13-15-22(16-14-20)21-9-5-3-6-10-21/h3-16,19,30H,17-18H2,1-2H3/t19-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Intra-Cellular Therapies, Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant full lenght human PDE4A using fluorescent labeled cAMP as substrate after 15 mins by IMAP assay				J Med Chem 59: 1149-64 (2016) BindingDB Entry DOI: 10.7270/Q2X068W7
					More data for this Ligand-Target Pair