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SMILES: Fc1cccnc1N1CCN(Cc2nc3ccccc3[nH]2)CC1

InChI Key: InChIKey=DIIMPNOBUZSQDU-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50150140   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
D(4) dopamine receptor


(Homo sapiens (Human))		BDBM50150140
PNG
(2-[4-(3-Fluoro-pyridin-2-yl)-piperazin-1-ylmethyl]...)
Show SMILES Fc1cccnc1N1CCN(Cc2nc3ccccc3[nH]2)CC1
Show InChI InChI=1S/C17H18FN5/c18-13-4-3-7-19-17(13)23-10-8-22(9-11-23)12-16-20-14-5-1-2-6-15(14)21-16/h1-7H,8-12H2,(H,20,21)
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Article
PubMed
n/an/an/an/a 24n/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro EC50 tested on HEK293 cells co-transfected with human Dopamine receptor D4.4 using FLIPR assay

J Med Chem 47: 3853-64 (2004)


Article DOI: 10.1021/jm030505a
BindingDB Entry DOI: 10.7270/Q24B3225
More data for this
Ligand-Target Pair