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SMILES: N#Cc1cccnc1N1CCN(Cc2nc3ccccc3[nH]2)CC1

InChI Key: InChIKey=HSEIIOCMMFLOGG-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50150145   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
D(4) dopamine receptor


(Homo sapiens (Human))		BDBM50150145
PNG
(2-[4-(1H-Benzoimidazol-2-ylmethyl)-piperazin-1-yl]...)
Show SMILES N#Cc1cccnc1N1CCN(Cc2nc3ccccc3[nH]2)CC1
Show InChI InChI=1S/C18H18N6/c19-12-14-4-3-7-20-18(14)24-10-8-23(9-11-24)13-17-21-15-5-1-2-6-16(15)22-17/h1-7H,8-11,13H2,(H,21,22)
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PC cid
PC sid
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Article
PubMed
n/an/an/an/a 13.9n/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro EC50 tested on HEK293 cells co-transfected with human Dopamine receptor D4.4 using FLIPR assay

J Med Chem 47: 3853-64 (2004)


Article DOI: 10.1021/jm030505a
BindingDB Entry DOI: 10.7270/Q24B3225
More data for this
Ligand-Target Pair