null

SMILES: CC(C)C[C@H](NC(=O)[C@H]1O[C@@H](CNC(=O)[C@@H](N)CSSC(C)(C)C)CC[C@@H]1OCc1ccccc1)C(O)=O

InChI Key: InChIKey=XUZDJAQFDBWHOZ-QCBQRGATSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50150662   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50150662 ((S)-2-({(2S,3S,6R)-6-[((R)-2-Amino-3-tert-butyldis...) Show SMILES CC(C)C[C@H](NC(=O)[C@H]1O[C@@H](CNC(=O)[C@@H](N)CSSC(C)(C)C)CC[C@@H]1OCc1ccccc1)C(O)=O Show InChI InChI=1S/C27H43N3O6S2/c1-17(2)13-21(26(33)34)30-25(32)23-22(35-15-18-9-7-6-8-10-18)12-11-19(36-23)14-29-24(31)20(28)16-37-38-27(3,4)5/h6-10,17,19-23H,11-16,28H2,1-5H3,(H,29,31)(H,30,32)(H,33,34)/t19-,20+,21+,22+,23+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of [3H]GGPP incorporation by Protein Geranylgeranyl transferase type I				J Med Chem 47: 3920-3 (2004) Article DOI: 10.1021/jm049927q BindingDB Entry DOI: 10.7270/Q2FT8MT5
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50150662 ((S)-2-({(2S,3S,6R)-6-[((R)-2-Amino-3-tert-butyldis...) Show SMILES CC(C)C[C@H](NC(=O)[C@H]1O[C@@H](CNC(=O)[C@@H](N)CSSC(C)(C)C)CC[C@@H]1OCc1ccccc1)C(O)=O Show InChI InChI=1S/C27H43N3O6S2/c1-17(2)13-21(26(33)34)30-25(32)23-22(35-15-18-9-7-6-8-10-18)12-11-19(36-23)14-29-24(31)20(28)16-37-38-27(3,4)5/h6-10,17,19-23H,11-16,28H2,1-5H3,(H,29,31)(H,30,32)(H,33,34)/t19-,20+,21+,22+,23+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of [3H]FPP incorporation by Protein Farnesyltransferase				J Med Chem 47: 3920-3 (2004) Article DOI: 10.1021/jm049927q BindingDB Entry DOI: 10.7270/Q2FT8MT5
					More data for this Ligand-Target Pair