BDBM50150684 (R)-8-(2,6-dimethoxyphenyl)-N,N-dimethylchroman-3-amine::CHEMBL183329::[(R)-8-(2,6-Dimethoxy-phenyl)-chroman-3-yl]-dimethyl-amine::[(S)-5-(2,6-Dimethoxy-phenyl)-1,2,3,4-tetrahydro-naphthalen-2-yl]-dimethyl-amine

SMILES: COc1cccc(OC)c1-c1cccc2C[C@H](COc12)N(C)C

InChI Key: InChIKey=KDVINCOUYWJUMK-CQSZACIVSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50150684   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50150684 ((R)-8-(2,6-dimethoxyphenyl)-N,N-dimethylchroman-3-...) Show SMILES COc1cccc(OC)c1-c1cccc2C[C@H](COc12)N(C)C |wD:16.22,(-5.36,2.24,;-4,1.49,;-2.67,2.28,;-2.7,3.82,;-1.37,4.59,;,3.84,;,2.29,;1.31,1.53,;2.64,2.29,;-1.34,1.53,;-1.34,-.01,;-2.67,-.78,;-2.67,-2.32,;-1.34,-3.09,;,-2.34,;1.31,-3.13,;2.67,-2.34,;2.67,-.78,;1.31,-.01,;,-.78,;4,-3.13,;4,-4.66,;5.35,-2.34,)| Show InChI InChI=1S/C19H23NO3/c1-20(2)14-11-13-7-5-8-15(19(13)23-12-14)18-16(21-3)9-6-10-17(18)22-4/h5-10,14H,11-12H2,1-4H3/t14-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cells				Bioorg Med Chem 18: 1958-67 (2010) Article DOI: 10.1016/j.bmc.2010.01.035 BindingDB Entry DOI: 10.7270/Q2S182M1
					More data for this Ligand-Target Pair
Serotonin (5-HT) receptor (Rattus norvegicus (rat))	BDBM50150684 ((R)-8-(2,6-dimethoxyphenyl)-N,N-dimethylchroman-3-...) Show SMILES COc1cccc(OC)c1-c1cccc2C[C@H](COc12)N(C)C |wD:16.22,(-5.36,2.24,;-4,1.49,;-2.67,2.28,;-2.7,3.82,;-1.37,4.59,;,3.84,;,2.29,;1.31,1.53,;2.64,2.29,;-1.34,1.53,;-1.34,-.01,;-2.67,-.78,;-2.67,-2.32,;-1.34,-3.09,;,-2.34,;1.31,-3.13,;2.67,-2.34,;2.67,-.78,;1.31,-.01,;,-.78,;4,-3.13,;4,-4.66,;5.35,-2.34,)| Show InChI InChI=1S/C19H23NO3/c1-20(2)14-11-13-7-5-8-15(19(13)23-12-14)18-16(21-3)9-6-10-17(18)22-4/h5-10,14H,11-12H2,1-4H3/t14-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Inhibition of [3H]-5-HT binding to rat 5-hydroxytryptamine 7 receptor				J Med Chem 47: 3927-30 (2004) Article DOI: 10.1021/jm0498102 BindingDB Entry DOI: 10.7270/Q2FQ9W2Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50150684 ((R)-8-(2,6-dimethoxyphenyl)-N,N-dimethylchroman-3-...) Show SMILES COc1cccc(OC)c1-c1cccc2C[C@H](COc12)N(C)C |wD:16.22,(-5.36,2.24,;-4,1.49,;-2.67,2.28,;-2.7,3.82,;-1.37,4.59,;,3.84,;,2.29,;1.31,1.53,;2.64,2.29,;-1.34,1.53,;-1.34,-.01,;-2.67,-.78,;-2.67,-2.32,;-1.34,-3.09,;,-2.34,;1.31,-3.13,;2.67,-2.34,;2.67,-.78,;1.31,-.01,;,-.78,;4,-3.13,;4,-4.66,;5.35,-2.34,)| Show InChI InChI=1S/C19H23NO3/c1-20(2)14-11-13-7-5-8-15(19(13)23-12-14)18-16(21-3)9-6-10-17(18)22-4/h5-10,14H,11-12H2,1-4H3/t14-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Inhibition of [3H]-8-OH-DPAT binding to rat 5-hydroxytryptamine 1A receptor				J Med Chem 47: 3927-30 (2004) Article DOI: 10.1021/jm0498102 BindingDB Entry DOI: 10.7270/Q2FQ9W2Z
					More data for this Ligand-Target Pair