BindingDB PrimarySearch

BDBM50150685 ((S)-5-Phenyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-amine::(S)-5-phenyl-N,N-dipropyl-1,2,3,4-tetrahydronaphthalen-2-amine::CHEMBL362540

SMILES: CCCN(CCC)[C@H]1CCc2c(C1)cccc2-c1ccccc1

InChI Key: InChIKey=BSNBARNQHMJQEX-FQEVSTJZSA-N

Data: 5 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50150685
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50150685 (((S)-5-Phenyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-...) Show SMILES CCCN(CCC)[C@H]1CCc2c(C1)cccc2-c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.870	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Inhibition of [3H]-8-OH-DPAT binding to rat 5-hydroxytryptamine 1A receptor				J Med Chem 47: 3927-30 (2004) Article DOI: 10.1021/jm0498102 BindingDB Entry DOI: 10.7270/Q2FQ9W2Z
Uppsala University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50150685 (((S)-5-Phenyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-...) Show SMILES CCCN(CCC)[C@H]1CCc2c(C1)cccc2-c1ccccc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.91	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cells				Bioorg Med Chem 18: 1958-67 (2010) Article DOI: 10.1016/j.bmc.2010.01.035 BindingDB Entry DOI: 10.7270/Q2S182M1
Universit£ d'Orl£ans Curated by ChEMBL					More data for this Ligand-Target Pair
Serotonin (5-HT) receptor (Rattus norvegicus (rat))	BDBM50150685 (((S)-5-Phenyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-...) Show SMILES CCCN(CCC)[C@H]1CCc2c(C1)cccc2-c1ccccc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Inhibition of [3H]-5-HT binding to rat 5-hydroxytryptamine 7 receptor				J Med Chem 47: 3927-30 (2004) Article DOI: 10.1021/jm0498102 BindingDB Entry DOI: 10.7270/Q2FQ9W2Z
Uppsala University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50150685 (((S)-5-Phenyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-...) Show SMILES CCCN(CCC)[C@H]1CCc2c(C1)cccc2-c1ccccc1 Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Displacement of [3H]-5-carboxamidotryptamine from human 5-HT1A receptor expressed in HEK293T cell membranes incubated for 90 mins by scintillation co...				Bioorg Med Chem 28: (2020)
Northeastern University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50150685 (((S)-5-Phenyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-...) Show SMILES CCCN(CCC)[C@H]1CCc2c(C1)cccc2-c1ccccc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Displacement of [3H]-5-carboxamidotryptamine from human 5-HT7A receptor expressed in HEK293 cell membranes incubated for 90 mins by scintillation cou...				Bioorg Med Chem 28: (2020)
Northeastern University Curated by ChEMBL					More data for this Ligand-Target Pair