BDBM50150791 3,6,8-Tribromo-dibenzo[1,4]dioxin-1-ol::CHEMBL185753::Spongiadioxin C

SMILES: Oc1cc(Br)cc2Oc3c(Br)cc(Br)cc3Oc12

InChI Key: InChIKey=XZPITRJUKODSMI-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50150791   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
12-Lipoxygenase (12-LOX) (Homo sapiens (Human))	BDBM50150791 (3,6,8-Tribromo-dibenzo[1,4]dioxin-1-ol | CHEMBL185...) Show SMILES Oc1cc(Br)cc2Oc3c(Br)cc(Br)cc3Oc12 Show InChI InChI=1S/C12H5Br3O3/c13-5-1-7(15)11-9(3-5)18-12-8(16)2-6(14)4-10(12)17-11/h1-4,16H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibitory effect on human platelet 12-lipoxygenase				J Med Chem 47: 4060-5 (2004) Article DOI: 10.1021/jm049872s BindingDB Entry DOI: 10.7270/Q2SX6CPV
					More data for this Ligand-Target Pair
Arachidonate 15-lipoxygenase (Homo sapiens (Human))	BDBM50150791 (3,6,8-Tribromo-dibenzo[1,4]dioxin-1-ol | CHEMBL185...) Show SMILES Oc1cc(Br)cc2Oc3c(Br)cc(Br)cc3Oc12 Show InChI InChI=1S/C12H5Br3O3/c13-5-1-7(15)11-9(3-5)18-12-8(16)2-6(14)4-10(12)17-11/h1-4,16H	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibitory effect on human reticulocyte 15-lipoxygenase				J Med Chem 47: 4060-5 (2004) Article DOI: 10.1021/jm049872s BindingDB Entry DOI: 10.7270/Q2SX6CPV
					More data for this Ligand-Target Pair