BDBM50150906 (E)-7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(E)-3-hydroxy-4-(3-trifluoromethyl-phenoxy)-but-1-enyl]-cyclopentyl}-hept-5-enoic acid isopropyl ester::CHEMBL185484
SMILES: CC(C)OC(=O)CCC\C=C\C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1\C=C\C(O)COc1cccc(c1)C(F)(F)F
InChI Key: InChIKey=MKPLKVHSHYCHOC-ZRUANHCFSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
PTGFR (BOVINE) | BDBM50150906 ((E)-7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(E)-3-hydrox...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 52 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Alcon Research, Ltd Curated by ChEMBL | Assay Description Binding affinity for Prostanoid FP receptor of bovine corpus luteum | Bioorg Med Chem Lett 14: 4525-8 (2004) Article DOI: 10.1016/j.bmcl.2004.06.037 BindingDB Entry DOI: 10.7270/Q2513ZZS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin F2-alpha receptor (Homo sapiens (Human)) | BDBM50150906 ((E)-7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(E)-3-hydrox...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.70 | n/a | n/a | n/a | n/a |
Alcon Research, Ltd Curated by ChEMBL | Assay Description Efficacy for stimulation of prostanoid FP receptor-linked phosphoinositide turnover in Swiss 3T3 mouse fibroblast cells | Bioorg Med Chem Lett 14: 4525-8 (2004) Article DOI: 10.1016/j.bmcl.2004.06.037 BindingDB Entry DOI: 10.7270/Q2513ZZS | |||||||||||
More data for this Ligand-Target Pair |