null

SMILES: C(Cc1c[nH]cn1)C1CCCNC1

InChI Key: InChIKey=ARRCCCIOHBCTKB-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50150944   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50150944 (CHEMBL153207) Show SMILES C(Cc1c[nH]cn1)C1CCCNC1 Show InChI InChI=1S/C10H17N3/c1-2-9(6-11-5-1)3-4-10-7-12-8-13-10/h7-9,11H,1-6H2,(H,12,13)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	182	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...				J Med Chem 59: 810-40 (2016) Article DOI: 10.1021/acs.jmedchem.5b00982 BindingDB Entry DOI: 10.7270/Q2XS5X8K
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50150944 (CHEMBL153207) Show SMILES C(Cc1c[nH]cn1)C1CCCNC1 Show InChI InChI=1S/C10H17N3/c1-2-9(6-11-5-1)3-4-10-7-12-8-13-10/h7-9,11H,1-6H2,(H,12,13)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	182	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vrije Universiteit Curated by ChEMBL					Assay Description Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H3 receptor				J Med Chem 46: 5445-57 (2003) Article DOI: 10.1021/jm030905y BindingDB Entry DOI: 10.7270/Q2FN18X0
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50150944 (CHEMBL153207) Show SMILES C(Cc1c[nH]cn1)C1CCCNC1 Show InChI InChI=1S/C10H17N3/c1-2-9(6-11-5-1)3-4-10-7-12-8-13-10/h7-9,11H,1-6H2,(H,12,13)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.00E+14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vrije Universiteit Curated by ChEMBL					Assay Description Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H4 receptor				J Med Chem 46: 5445-57 (2003) Article DOI: 10.1021/jm030905y BindingDB Entry DOI: 10.7270/Q2FN18X0
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50150944 (CHEMBL153207) Show SMILES C(Cc1c[nH]cn1)C1CCCNC1 Show InChI InChI=1S/C10H17N3/c1-2-9(6-11-5-1)3-4-10-7-12-8-13-10/h7-9,11H,1-6H2,(H,12,13)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	513	n/a	n/a	n/a	n/a
Vrije Universiteit Curated by ChEMBL					Assay Description Inhibitory activity determined by the inhibition of cAMP- stimulated beta-galactosidase transcription in SK-N-MC cells expressing the human Histamine...				J Med Chem 46: 5445-57 (2003) Article DOI: 10.1021/jm030905y BindingDB Entry DOI: 10.7270/Q2FN18X0
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50150944 (CHEMBL153207) Show SMILES C(Cc1c[nH]cn1)C1CCCNC1 Show InChI InChI=1S/C10H17N3/c1-2-9(6-11-5-1)3-4-10-7-12-8-13-10/h7-9,11H,1-6H2,(H,12,13)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.04E+3	n/a	n/a	n/a	n/a
Vrije Universiteit Curated by ChEMBL					Assay Description Inhibitory activity determined by the inhibition of cAMP- stimulated beta-galactosidase transcription in SK-N-MC cells expressing the human Histamine...				J Med Chem 46: 5445-57 (2003) Article DOI: 10.1021/jm030905y BindingDB Entry DOI: 10.7270/Q2FN18X0
					More data for this Ligand-Target Pair