BDBM50151034 CHEMBL3771317

SMILES: CCCS(=O)(=O)N(Cc1ccccc1)c1nc(ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1)C(F)(F)F

InChI Key: InChIKey=GQVRHQYRFCEEOS-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50151034   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50151034 (CHEMBL3771317) Show SMILES CCCS(=O)(=O)N(Cc1ccccc1)c1nc(ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1)C(F)(F)F Show InChI InChI=1S/C27H30F4N4O5S2/c1-4-14-42(39,40)35(17-19-8-6-5-7-9-19)25-21(11-13-24(33-25)27(29,30)31)16-32-26(36)18(2)20-10-12-23(22(28)15-20)34-41(3,37)38/h5-13,15,18,34H,4,14,16-17H2,1-3H3,(H,32,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	3.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of capsaicin-induced (45)Ca2+ uptake after 5 mins by liquid scintill...				Bioorg Med Chem 24: 1231-40 (2016) BindingDB Entry DOI: 10.7270/Q25D8TP7
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50151034 (CHEMBL3771317) Show SMILES CCCS(=O)(=O)N(Cc1ccccc1)c1nc(ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1)C(F)(F)F Show InChI InChI=1S/C27H30F4N4O5S2/c1-4-14-42(39,40)35(17-19-8-6-5-7-9-19)25-21(11-13-24(33-25)27(29,30)31)16-32-26(36)18(2)20-10-12-23(22(28)15-20)34-41(3,37)38/h5-13,15,18,34H,4,14,16-17H2,1-3H3,(H,32,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	8.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Displacement of [3H]RTX from human TRPV1 expressed in CHO cells after 60 mins by scintillation counting analysis				Bioorg Med Chem 24: 1231-40 (2016) BindingDB Entry DOI: 10.7270/Q25D8TP7
					More data for this Ligand-Target Pair