BDBM50151096 CHEMBL3769689
SMILES: CCCOc1ccc(COC(=O)N[C@H]2CNC2=O)cc1
InChI Key: InChIKey=YPMNHNKWLFDHSJ-LBPRGKRZSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human)) | BDBM50151096 (CHEMBL3769689) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a | n/a |
Italian Institute of Technology Curated by ChEMBL | Assay Description Inhibition of GST-tagged human BRD4 bromodomain2 using H4KAc 5/8/12/16 peptide as substrate incubated overnight by HTRF assay | Eur J Med Chem 111: 138-59 (2016) BindingDB Entry DOI: 10.7270/Q2GQ70MX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acid ceramidase (AC) (Homo sapiens (Human)) | BDBM50151096 (CHEMBL3769689) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 2.41E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Italian Institute of Technology Curated by ChEMBL | Assay Description Inhibition of human acid ceramidase by UPLC/MS analysis | Eur J Med Chem 111: 138-59 (2016) BindingDB Entry DOI: 10.7270/Q2GQ70MX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human)) | BDBM50151096 (CHEMBL3769689) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
Italian Institute of Technology Curated by ChEMBL | Assay Description Inhibition of recombinant human NAAA expressed in HEK293 cells after 30 mins by UPLC/MS analysis | Eur J Med Chem 111: 138-59 (2016) BindingDB Entry DOI: 10.7270/Q2GQ70MX | |||||||||||
More data for this Ligand-Target Pair |