BDBM50151121 CHEMBL3770852

SMILES: COc1ccc(CN(c2nc(ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)C(F)(F)F)S(=O)(=O)c2ccccc2)cc1

InChI Key: InChIKey=HSFMUBAUTKMLLS-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50151121   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50151121 (CHEMBL3770852) Show SMILES COc1ccc(CN(c2nc(ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)C(F)(F)F)S(=O)(=O)c2ccccc2)cc1 Show InChI InChI=1S/C31H30F4N4O6S2/c1-20(22-11-15-27(26(32)17-22)38-46(3,41)42)30(40)36-18-23-12-16-28(31(33,34)35)37-29(23)39(19-21-9-13-24(45-2)14-10-21)47(43,44)25-7-5-4-6-8-25/h4-17,20,38H,18-19H2,1-3H3,(H,36,40)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Displacement of [3H]RTX from human TRPV1 expressed in CHO cells after 60 mins by scintillation counting analysis				Bioorg Med Chem 24: 1231-40 (2016) BindingDB Entry DOI: 10.7270/Q25D8TP7
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50151121 (CHEMBL3770852) Show SMILES COc1ccc(CN(c2nc(ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)C(F)(F)F)S(=O)(=O)c2ccccc2)cc1 Show InChI InChI=1S/C31H30F4N4O6S2/c1-20(22-11-15-27(26(32)17-22)38-46(3,41)42)30(40)36-18-23-12-16-28(31(33,34)35)37-29(23)39(19-21-9-13-24(45-2)14-10-21)47(43,44)25-7-5-4-6-8-25/h4-17,20,38H,18-19H2,1-3H3,(H,36,40)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Displacement of [3H]RTX from human TRPV1 expressed in CHO cells after 60 mins by scintillation counting analysis				Bioorg Med Chem 24: 1231-40 (2016) BindingDB Entry DOI: 10.7270/Q25D8TP7
					More data for this Ligand-Target Pair