BDBM50151162 (S)-3-(2-Chloro-phenyl)-1-(2-diethylamino-ethyl)-3-hydroxy-2-oxo-4-trifluoromethyl-2,3-dihydro-1H-indole-6-carboxylic acid amide::CHEMBL360227

SMILES: CCN(CC)CCN1C(=O)[C@](O)(c2c1cc(cc2C(F)(F)F)C(N)=O)c1ccccc1Cl

InChI Key: InChIKey=YSSPGXCFFITNCE-OAQYLSRUSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50151162   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ghrelin receptor (Homo sapiens (Human))	BDBM50151162 ((S)-3-(2-Chloro-phenyl)-1-(2-diethylamino-ethyl)-3...) Show SMILES CCN(CC)CCN1C(=O)[C@](O)(c2c1cc(cc2C(F)(F)F)C(N)=O)c1ccccc1Cl Show InChI InChI=1S/C22H23ClF3N3O3/c1-3-28(4-2)9-10-29-17-12-13(19(27)30)11-15(22(24,25)26)18(17)21(32,20(29)31)14-7-5-6-8-16(14)23/h5-8,11-12,32H,3-4,9-10H2,1-2H3,(H2,27,30)/t21-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Life Science Research Curated by ChEMBL					Assay Description Binding affinity for human growth hormone secretagogue receptor was determined using [125I]-ghrelin				J Med Chem 47: 4286-90 (2004) Article DOI: 10.1021/jm040103i BindingDB Entry DOI: 10.7270/Q2CR5SV7
					More data for this Ligand-Target Pair
Ghrelin receptor (Homo sapiens (Human))	BDBM50151162 ((S)-3-(2-Chloro-phenyl)-1-(2-diethylamino-ethyl)-3...) Show SMILES CCN(CC)CCN1C(=O)[C@](O)(c2c1cc(cc2C(F)(F)F)C(N)=O)c1ccccc1Cl Show InChI InChI=1S/C22H23ClF3N3O3/c1-3-28(4-2)9-10-29-17-12-13(19(27)30)11-15(22(24,25)26)18(17)21(32,20(29)31)14-7-5-6-8-16(14)23/h5-8,11-12,32H,3-4,9-10H2,1-2H3,(H2,27,30)/t21-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Sumitomo Pharmaceuticals Co., Ltd Curated by ChEMBL					Assay Description Inhibition of [125I]ghrelin binding to human recombinant ghrelin receptor membrane preparation				Bioorg Med Chem Lett 15: 1789-92 (2005) Article DOI: 10.1016/j.bmcl.2005.02.042 BindingDB Entry DOI: 10.7270/Q24J0FWD
					More data for this Ligand-Target Pair
Ghrelin receptor (Homo sapiens (Human))	BDBM50151162 ((S)-3-(2-Chloro-phenyl)-1-(2-diethylamino-ethyl)-3...) Show SMILES CCN(CC)CCN1C(=O)[C@](O)(c2c1cc(cc2C(F)(F)F)C(N)=O)c1ccccc1Cl Show InChI InChI=1S/C22H23ClF3N3O3/c1-3-28(4-2)9-10-29-17-12-13(19(27)30)11-15(22(24,25)26)18(17)21(32,20(29)31)14-7-5-6-8-16(14)23/h5-8,11-12,32H,3-4,9-10H2,1-2H3,(H2,27,30)/t21-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Sumitomo Pharmaceuticals Co., Ltd Curated by ChEMBL					Assay Description Inhibition of [125I]ghrelin binding to human recombinant ghrelin receptor membrane preparation				Bioorg Med Chem Lett 15: 1789-92 (2005) Article DOI: 10.1016/j.bmcl.2005.02.042 BindingDB Entry DOI: 10.7270/Q24J0FWD
					More data for this Ligand-Target Pair