BDBM50151226 4-[(3-Butyl-5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-cyclopropylidene-methyl]-benzoic acid::CHEMBL188638

SMILES: [#6]-[#6]-[#6]-[#6]-c1cc2c(cc1\[#6](=[#6]-1\[#6]-[#6]-1)-c1ccc(cc1)-[#6](-[#8])=O)C([#6])([#6])[#6]-[#6]C2([#6])[#6]

InChI Key: InChIKey=QCWNVPMGGVCEIT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50151226   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM50151226 (4-[(3-Butyl-5,5,8,8-tetramethyl-5,6,7,8-tetrahydro...) Show SMILES [#6]-[#6]-[#6]-[#6]-c1cc2c(cc1\[#6](=[#6]-1\[#6]-[#6]-1)-c1ccc(cc1)-[#6](-[#8])=O)C([#6])([#6])[#6]-[#6]C2([#6])[#6] Show InChI InChI=1S/C29H36O2/c1-6-7-8-22-17-24-25(29(4,5)16-15-28(24,2)3)18-23(22)26(19-9-10-19)20-11-13-21(14-12-20)27(30)31/h11-14,17-18H,6-10,15-16H2,1-5H3,(H,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Institute Curated by ChEMBL					Assay Description Inhibition of [3H]-9-cis-retinoic acid binding to human retinoid X receptor alpha ligand-binding domain expressed in E. coli				J Med Chem 47: 4360-72 (2004) Article DOI: 10.1021/jm030651g BindingDB Entry DOI: 10.7270/Q24749B0
					More data for this Ligand-Target Pair