BDBM50151372 CHEMBL3774994

SMILES: CN(c1cccc(OCCCCC(=O)NO)c1)c1nc(C)nc2ccccc12

InChI Key: InChIKey=VAVRSOISHAFQEV-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50151372   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cereblon/Histone deacetylase 1 (Homo sapiens (Human))	BDBM50151372 (CHEMBL3774994) Show SMILES CN(c1cccc(OCCCCC(=O)NO)c1)c1nc(C)nc2ccccc12 Show InChI InChI=1S/C21H24N4O3/c1-15-22-19-11-4-3-10-18(19)21(23-15)25(2)16-8-7-9-17(14-16)28-13-6-5-12-20(26)24-27/h3-4,7-11,14,27H,5-6,12-13H2,1-2H3,(H,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	306	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...				J Med Chem 59: 1455-70 (2016) BindingDB Entry DOI: 10.7270/Q2T155H3
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50151372 (CHEMBL3774994) Show SMILES CN(c1cccc(OCCCCC(=O)NO)c1)c1nc(C)nc2ccccc12 Show InChI InChI=1S/C21H24N4O3/c1-15-22-19-11-4-3-10-18(19)21(23-15)25(2)16-8-7-9-17(14-16)28-13-6-5-12-20(26)24-27/h3-4,7-11,14,27H,5-6,12-13H2,1-2H3,(H,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of KDM5C (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...				J Med Chem 59: 1455-70 (2016) BindingDB Entry DOI: 10.7270/Q2T155H3
					More data for this Ligand-Target Pair
Cereblon/Histone deacetylase 6 (Homo sapiens (Human))	BDBM50151372 (CHEMBL3774994) Show SMILES CN(c1cccc(OCCCCC(=O)NO)c1)c1nc(C)nc2ccccc12 Show InChI InChI=1S/C21H24N4O3/c1-15-22-19-11-4-3-10-18(19)21(23-15)25(2)16-8-7-9-17(14-16)28-13-6-5-12-20(26)24-27/h3-4,7-11,14,27H,5-6,12-13H2,1-2H3,(H,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...				J Med Chem 59: 1455-70 (2016) BindingDB Entry DOI: 10.7270/Q2T155H3
					More data for this Ligand-Target Pair