BDBM50151381 CHEMBL3775409

SMILES: CN(c1ccc(OCCCCCC(=O)NO)cc1)c1nc(C)nc2ccccc12

InChI Key: InChIKey=YHQAMQHTTOJBPC-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50151381   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50151381 (CHEMBL3775409) Show SMILES CN(c1ccc(OCCCCCC(=O)NO)cc1)c1nc(C)nc2ccccc12 Show InChI InChI=1S/C22H26N4O3/c1-16-23-20-9-6-5-8-19(20)22(24-16)26(2)17-11-13-18(14-12-17)29-15-7-3-4-10-21(27)25-28/h5-6,8-9,11-14,28H,3-4,7,10,15H2,1-2H3,(H,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	272	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...				J Med Chem 59: 1455-70 (2016) BindingDB Entry DOI: 10.7270/Q2T155H3
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50151381 (CHEMBL3775409) Show SMILES CN(c1ccc(OCCCCCC(=O)NO)cc1)c1nc(C)nc2ccccc12 Show InChI InChI=1S/C22H26N4O3/c1-16-23-20-9-6-5-8-19(20)22(24-16)26(2)17-11-13-18(14-12-17)29-15-7-3-4-10-21(27)25-28/h5-6,8-9,11-14,28H,3-4,7,10,15H2,1-2H3,(H,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.51E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of human N-terminal His-tagged KDM4A (1 to 359 residues) expressed in Escherichia coli using biotin-H3K9me3 as substrate preincubated for ...				J Med Chem 59: 1455-70 (2016) BindingDB Entry DOI: 10.7270/Q2T155H3
					More data for this Ligand-Target Pair
Cereblon/Histone deacetylase 6 (Homo sapiens (Human))	BDBM50151381 (CHEMBL3775409) Show SMILES CN(c1ccc(OCCCCCC(=O)NO)cc1)c1nc(C)nc2ccccc12 Show InChI InChI=1S/C22H26N4O3/c1-16-23-20-9-6-5-8-19(20)22(24-16)26(2)17-11-13-18(14-12-17)29-15-7-3-4-10-21(27)25-28/h5-6,8-9,11-14,28H,3-4,7,10,15H2,1-2H3,(H,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of KDM5C (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...				J Med Chem 59: 1455-70 (2016) BindingDB Entry DOI: 10.7270/Q2T155H3
					More data for this Ligand-Target Pair