BDBM50151404 CHEMBL3774894

SMILES: OC(=O)c1ccnc(c1)-c1cc(NCc2ccc(Br)cc2)ccc1O

InChI Key: InChIKey=AKLBBPABHKTNRM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50151404   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM50151404 (CHEMBL3774894) Show SMILES OC(=O)c1ccnc(c1)-c1cc(NCc2ccc(Br)cc2)ccc1O Show InChI InChI=1S/C19H15BrN2O3/c20-14-3-1-12(2-4-14)11-22-15-5-6-18(23)16(10-15)17-9-13(19(24)25)7-8-21-17/h1-10,22-23H,11H2,(H,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of N-terminal His6-tagged KDM4C (1 to 352 residues) (unknown origin) expressed in Escherichia coli Rosetta 2(DE3)pLysS using biotinylated ...				J Med Chem 59: 1580-98 (2016) BindingDB Entry DOI: 10.7270/Q2P84DRX
					More data for this Ligand-Target Pair