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BDBM50151404 CHEMBL3774894

SMILES: OC(=O)c1ccnc(c1)-c1cc(NCc2ccc(Br)cc2)ccc1O

InChI Key: InChIKey=AKLBBPABHKTNRM-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50151404   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lysine-specific demethylase 4C


(Homo sapiens (Human))
BDBM50151404
PNG
(CHEMBL3774894)
Show SMILES OC(=O)c1ccnc(c1)-c1cc(NCc2ccc(Br)cc2)ccc1O
Show InChI InChI=1S/C19H15BrN2O3/c20-14-3-1-12(2-4-14)11-22-15-5-6-18(23)16(10-15)17-9-13(19(24)25)7-8-21-17/h1-10,22-23H,11H2,(H,24,25)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

PubMed
n/an/a 2.50E+3n/an/an/an/an/an/a



University of Oxford

Curated by ChEMBL


Assay Description
Inhibition of N-terminal His6-tagged KDM4C (1 to 352 residues) (unknown origin) expressed in Escherichia coli Rosetta 2(DE3)pLysS using biotinylated ...


J Med Chem 59: 1580-98 (2016)


BindingDB Entry DOI: 10.7270/Q2P84DRX
More data for this
Ligand-Target Pair