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SMILES: N[C@@]1([C@H]2[C@@H](C[C@H]1OCc1cccc(Cl)c1Cl)[C@]2(F)C(O)=O)C(O)=O

InChI Key: InChIKey=HJAGDJXFCQXTFE-WJRHDCNNSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50151463   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 2


(Homo sapiens (Human))		BDBM50151463
PNG
((1R,2R,3R,5R,6R)-2-Amino-3-(2,3-dichloro-benzyloxy...)
Show SMILES N[C@@]1([C@H]2[C@@H](C[C@H]1OCc1cccc(Cl)c1Cl)[C@]2(F)C(O)=O)C(O)=O
Show InChI InChI=1S/C15H14Cl2FNO5/c16-8-3-1-2-6(10(8)17)5-24-9-4-7-11(14(7,18)12(20)21)15(9,19)13(22)23/h1-3,7,9,11H,4-5,19H2,(H,20,21)(H,22,23)/t7-,9-,11+,14-,15+/m1/s1
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Similars
Article
PubMed
 4.35n/an/an/an/an/an/an/an/a



Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Binding affinity towards metabotropic glutamate receptor 2 of rat expressed in CHO cells was determined by using [3H]-MGS0008

J Med Chem 47: 4570-87 (2004)


Article DOI: 10.1021/jm0400294
BindingDB Entry DOI: 10.7270/Q2GH9HFK
More data for this
Ligand-Target Pair