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BDBM50151468 (1R,2R,3R,5R,6R)-2-Amino-3-(2-chloro-benzyloxy)-6-fluoro-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid::CHEMBL362092

SMILES: N[C@@]1([C@H]2[C@@H](C[C@H]1OCc1ccccc1Cl)[C@]2(F)C(O)=O)C(O)=O

InChI Key: InChIKey=DMEPGOCTVGPRHE-YUVXLREMSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50151468   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 2


(Homo sapiens (Human))
BDBM50151468
PNG
((1R,2R,3R,5R,6R)-2-Amino-3-(2-chloro-benzyloxy)-6-...)
Show SMILES N[C@@]1([C@H]2[C@@H](C[C@H]1OCc1ccccc1Cl)[C@]2(F)C(O)=O)C(O)=O
Show InChI InChI=1S/C15H15ClFNO5/c16-9-4-2-1-3-7(9)6-23-10-5-8-11(14(8,17)12(19)20)15(10,18)13(21)22/h1-4,8,10-11H,5-6,18H2,(H,19,20)(H,21,22)/t8-,10-,11+,14-,15+/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
4.99n/an/an/an/an/an/an/an/a



Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Binding affinity towards metabotropic glutamate receptor 2 of rat expressed in CHO cells was determined by using [3H]-MGS0008


J Med Chem 47: 4570-87 (2004)


Article DOI: 10.1021/jm0400294
BindingDB Entry DOI: 10.7270/Q2GH9HFK
More data for this
Ligand-Target Pair