BDBM50151659 CHEMBL3775244
SMILES: COc1ccc(cc1OC)C1CC(=NN1c1nc(cs1)-c1ccc(cc1)N1C(=O)c2ccccc2C1=O)c1cccs1
InChI Key: InChIKey=UOEGYWWWSHVNGP-UHFFFAOYSA-N
Data: 4 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Histone acetyltransferase p300 (Homo sapiens (Human)) | BDBM50151659 (CHEMBL3775244) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Freiburg Curated by ChEMBL | Assay Description Inhibition of p300 (unknown origin) using N-terminal histone H4-20 peptide substrate incubated for 10 mins by liquid scintillation counting method in... | J Med Chem 59: 1249-70 (2016) BindingDB Entry DOI: 10.7270/Q2DV1MRN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Spermidine synthase (Sus scrofa) | BDBM50151659 (CHEMBL3775244) | UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.90E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Freiburg Curated by ChEMBL | Assay Description Inhibition of yeast ESA1 using N-terminal histone H3 substrate by radiometric filter binding based virtual screen in presence of [3H]acetyl-CoA | J Med Chem 59: 1249-70 (2016) BindingDB Entry DOI: 10.7270/Q2DV1MRN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone acetyltransferase KAT5 (Homo sapiens (Human)) | BDBM50151659 (CHEMBL3775244) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.49E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Freiburg Curated by ChEMBL | Assay Description Inhibition of full length TIP60 (unknown origin) expressed in Escherichia coli using N-terminal histone H4-20 peptide substrate incubated for 10 mins... | J Med Chem 59: 1249-70 (2016) BindingDB Entry DOI: 10.7270/Q2DV1MRN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone acetyltransferase PCAF (Homo sapiens (Human)) | BDBM50151659 (CHEMBL3775244) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Freiburg Curated by ChEMBL | Assay Description Inhibition of PCAF (unknown origin) using N-terminal histone H3-20 peptide substrate incubated for 3.5 mins by liquid scintillation counting method i... | J Med Chem 59: 1249-70 (2016) BindingDB Entry DOI: 10.7270/Q2DV1MRN | |||||||||||
More data for this Ligand-Target Pair |