BDBM50151957 3-[4-(4-Benzo[1,3]dioxol-5-yl-3,6-dihydro-2H-pyridin-1-yl)-butyl]-5-methoxy-1H-indole::CHEMBL186814

SMILES: COc1ccc2[nH]cc(CCCCN3CCC(=CC3)c3ccc4OCOc4c3)c2c1

InChI Key: InChIKey=UNWPOGGIFDUAHY-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50151957   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50151957 (3-[4-(4-Benzo[1,3]dioxol-5-yl-3,6-dihydro-2H-pyrid...) Show SMILES COc1ccc2[nH]cc(CCCCN3CCC(=CC3)c3ccc4OCOc4c3)c2c1 |c:16| Show InChI InChI=1S/C25H28N2O3/c1-28-21-6-7-23-22(15-21)20(16-26-23)4-2-3-11-27-12-9-18(10-13-27)19-5-8-24-25(14-19)30-17-29-24/h5-9,14-16,26H,2-4,10-13,17H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
Merck KGaA Curated by ChEMBL					Assay Description Displacement of [3H]-spiperone from dopamine D2 receptor of rat striatal membranes				J Med Chem 47: 4677-83 (2004) Article DOI: 10.1021/jm040792y BindingDB Entry DOI: 10.7270/Q28S4PCR
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50151957 (3-[4-(4-Benzo[1,3]dioxol-5-yl-3,6-dihydro-2H-pyrid...) Show SMILES COc1ccc2[nH]cc(CCCCN3CCC(=CC3)c3ccc4OCOc4c3)c2c1 |c:16| Show InChI InChI=1S/C25H28N2O3/c1-28-21-6-7-23-22(15-21)20(16-26-23)4-2-3-11-27-12-9-18(10-13-27)19-5-8-24-25(14-19)30-17-29-24/h5-9,14-16,26H,2-4,10-13,17H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
Merck KGaA Curated by ChEMBL					Assay Description Inhibition of 8-OH DPAT bindign to rat hydroxytryptamine 1A receptor expressed in CHO cells				J Med Chem 47: 4677-83 (2004) Article DOI: 10.1021/jm040792y BindingDB Entry DOI: 10.7270/Q28S4PCR
					More data for this Ligand-Target Pair