null

SMILES: CCCN(CCC)c1c(F)c(C)nc2c(c(C)nn12)-c1cnc(cc1C)N(C)C

InChI Key: InChIKey=KIXFJYQVZDZLCL-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50152163   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50152163 (CHEMBL444614 | [3-(6-Dimethylamino-4-methyl-pyridi...) Show SMILES CCCN(CCC)c1c(F)c(C)nc2c(c(C)nn12)-c1cnc(cc1C)N(C)C |(3.8,5.58,;4.27,4.12,;3.26,2.97,;3.74,1.51,;5.25,1.2,;6.27,2.35,;7.77,2.04,;2.71,.36,;3.2,-1.1,;4.71,-1.41,;2.17,-2.24,;2.66,-3.7,;.68,-1.92,;.19,-.47,;-1.2,.16,;-1.06,1.69,;-2.21,2.7,;.45,2,;1.22,.67,;-2.53,-.63,;-2.53,-2.17,;-3.87,-2.94,;-5.2,-2.17,;-5.2,-.63,;-3.87,.14,;-3.88,1.69,;-6.54,-2.94,;-6.54,-4.48,;-7.87,-2.17,)| Show InChI InChI=1S/C22H31FN6/c1-8-10-28(11-9-2)22-20(23)16(5)25-21-19(15(4)26-29(21)22)17-13-24-18(27(6)7)12-14(17)3/h12-13H,8-11H2,1-7H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of [125I]-o-CRF binding to CHO cells expressing human CRF1 receptor				J Med Chem 47: 4787-98 (2004) Article DOI: 10.1021/jm040058e BindingDB Entry DOI: 10.7270/Q2N29WDR
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50152163 (CHEMBL444614 | [3-(6-Dimethylamino-4-methyl-pyridi...) Show SMILES CCCN(CCC)c1c(F)c(C)nc2c(c(C)nn12)-c1cnc(cc1C)N(C)C |(3.8,5.58,;4.27,4.12,;3.26,2.97,;3.74,1.51,;5.25,1.2,;6.27,2.35,;7.77,2.04,;2.71,.36,;3.2,-1.1,;4.71,-1.41,;2.17,-2.24,;2.66,-3.7,;.68,-1.92,;.19,-.47,;-1.2,.16,;-1.06,1.69,;-2.21,2.7,;.45,2,;1.22,.67,;-2.53,-.63,;-2.53,-2.17,;-3.87,-2.94,;-5.2,-2.17,;-5.2,-.63,;-3.87,.14,;-3.88,1.69,;-6.54,-2.94,;-6.54,-4.48,;-7.87,-2.17,)| Show InChI InChI=1S/C22H31FN6/c1-8-10-28(11-9-2)22-20(23)16(5)25-21-19(15(4)26-29(21)22)17-13-24-18(27(6)7)12-14(17)3/h12-13H,8-11H2,1-7H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of [125I]-o-CRF binding to CHO cells expressing human CRF1 receptor				J Med Chem 47: 4787-98 (2004) Article DOI: 10.1021/jm040058e BindingDB Entry DOI: 10.7270/Q2N29WDR
					More data for this Ligand-Target Pair