BDBM50152189 Phosphoric acid 5-(6-amino-purin-9-yl)-2-phosphonooxymethyl-tetrahydro-furan-3-yl ester 4-(6-amino-purin-9-yl)-tetrahydro-furan-2-ylmethyl ester::[4-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methyl [5-(6-amino-9H-purin-9-yl)-2-[(phosphonatooxy)methyl]oxolan-3-yl] phosphate

SMILES: Nc1ccn(C2COC(COP([O-])(=O)OC3CC(OC3COP([O-])([O-])=O)n3cnc4c(N)ncnc34)C2O)c(=O)n1

InChI Key: InChIKey=LPGFNCONVZCCCG-UHFFFAOYSA-K

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50152189   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50152189 (Phosphoric acid 5-(6-amino-purin-9-yl)-2-phosphono...) Show SMILES Nc1ccn(C2COC(COP([O-])(=O)OC3CC(OC3COP([O-])([O-])=O)n3cnc4c(N)ncnc34)C2O)c(=O)n1 Show InChI InChI=1S/C19H26N8O12P2/c20-13-1-2-26(19(29)25-13)9-4-35-12(16(9)28)6-37-41(33,34)39-10-3-14(38-11(10)5-36-40(30,31)32)27-8-24-15-17(21)22-7-23-18(15)27/h1-2,7-12,14,16,28H,3-6H2,(H,33,34)(H2,20,25,29)(H2,21,22,23)(H2,30,31,32)/p-3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
University of Georgia Curated by ChEMBL					Assay Description Inhibitory activity against 3'-processing step in wild-type HIV-1 integrase was determined using 21-mer oligonucleotide substrate				Bioorg Med Chem Lett 14: 4815-7 (2004) Article DOI: 10.1016/j.bmcl.2004.07.050 BindingDB Entry DOI: 10.7270/Q2QV3N8B
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50152189 (Phosphoric acid 5-(6-amino-purin-9-yl)-2-phosphono...) Show SMILES Nc1ccn(C2COC(COP([O-])(=O)OC3CC(OC3COP([O-])([O-])=O)n3cnc4c(N)ncnc34)C2O)c(=O)n1 Show InChI InChI=1S/C19H26N8O12P2/c20-13-1-2-26(19(29)25-13)9-4-35-12(16(9)28)6-37-41(33,34)39-10-3-14(38-11(10)5-36-40(30,31)32)27-8-24-15-17(21)22-7-23-18(15)27/h1-2,7-12,14,16,28H,3-6H2,(H,33,34)(H2,20,25,29)(H2,21,22,23)(H2,30,31,32)/p-3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Georgia Curated by ChEMBL					Assay Description Inhibitory activity against strand transfer in wild-type HIV-1 integrase was determined using 21-mer oligonucleotide substrate				Bioorg Med Chem Lett 14: 4815-7 (2004) Article DOI: 10.1016/j.bmcl.2004.07.050 BindingDB Entry DOI: 10.7270/Q2QV3N8B
					More data for this Ligand-Target Pair