BDBM50152190 Phosphoric acid 5-(6-amino-purin-9-yl)-2-phosphonooxymethyl-tetrahydro-furan-3-yl ester 4-(6-amino-purin-9-yl)-tetrahydro-furan-2-ylmethyl ester::[5-(6-amino-9H-purin-9-yl)-2-[(phosphonatooxy)methyl]oxolan-3-yl] [4-(6-amino-9H-purin-9-yl)oxolan-2-yl]methyl phosphate

SMILES: Nc1ncnc2n(cnc12)C1COC(COP([O-])(=O)OC2CC(OC2COP([O-])([O-])=O)n2cnc3c(N)ncnc23)C1

InChI Key: InChIKey=CBSKDKCHKOJBHK-UHFFFAOYSA-K

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50152190   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50152190 (Phosphoric acid 5-(6-amino-purin-9-yl)-2-phosphono...) Show SMILES Nc1ncnc2n(cnc12)C1COC(COP([O-])(=O)OC2CC(OC2COP([O-])([O-])=O)n2cnc3c(N)ncnc23)C1 Show InChI InChI=1S/C20H26N10O10P2/c21-17-15-19(25-6-23-17)29(8-27-15)10-1-11(36-3-10)4-38-42(34,35)40-12-2-14(39-13(12)5-37-41(31,32)33)30-9-28-16-18(22)24-7-26-20(16)30/h6-14H,1-5H2,(H,34,35)(H2,21,23,25)(H2,22,24,26)(H2,31,32,33)/p-3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.14E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Georgia Curated by ChEMBL					Assay Description Inhibitory activity against strand transfer in wild-type HIV-1 integrase was determined using 21-mer oligonucleotide substrate				Bioorg Med Chem Lett 14: 4815-7 (2004) Article DOI: 10.1016/j.bmcl.2004.07.050 BindingDB Entry DOI: 10.7270/Q2QV3N8B
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50152190 (Phosphoric acid 5-(6-amino-purin-9-yl)-2-phosphono...) Show SMILES Nc1ncnc2n(cnc12)C1COC(COP([O-])(=O)OC2CC(OC2COP([O-])([O-])=O)n2cnc3c(N)ncnc23)C1 Show InChI InChI=1S/C20H26N10O10P2/c21-17-15-19(25-6-23-17)29(8-27-15)10-1-11(36-3-10)4-38-42(34,35)40-12-2-14(39-13(12)5-37-41(31,32)33)30-9-28-16-18(22)24-7-26-20(16)30/h6-14H,1-5H2,(H,34,35)(H2,21,23,25)(H2,22,24,26)(H2,31,32,33)/p-3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
University of Georgia Curated by ChEMBL					Assay Description Inhibitory activity against 3'-processing step in wild-type HIV-1 integrase was determined using 21-mer oligonucleotide substrate				Bioorg Med Chem Lett 14: 4815-7 (2004) Article DOI: 10.1016/j.bmcl.2004.07.050 BindingDB Entry DOI: 10.7270/Q2QV3N8B
					More data for this Ligand-Target Pair