BDBM50152321 (4-Hydroxy-1-tetradecyl-piperidin-4-yl)-methyl-phosphinic acid::CHEMBL187645

SMILES: CCCCCCCCCCCCCCN1CCC(O)(CC1)P(C)(O)=O

InChI Key: InChIKey=FXUWQRWIQRYKKB-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50152321   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sphingosine 1-phosphate receptor 2 (Homo sapiens (Human))	BDBM50152321 ((4-Hydroxy-1-tetradecyl-piperidin-4-yl)-methyl-pho...) Show SMILES CCCCCCCCCCCCCCN1CCC(O)(CC1)P(C)(O)=O Show InChI InChI=1S/C20H42NO3P/c1-3-4-5-6-7-8-9-10-11-12-13-14-17-21-18-15-20(22,16-19-21)25(2,23)24/h22H,3-19H2,1-2H3,(H,23,24)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [33P]-S1P binding to human Sphingosine 1-phosphate receptor 2 expressed on CHO cell membranes				Bioorg Med Chem Lett 14: 4861-6 (2004) Article DOI: 10.1016/j.bmcl.2004.07.049 BindingDB Entry DOI: 10.7270/Q2BK1D38
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50152321 ((4-Hydroxy-1-tetradecyl-piperidin-4-yl)-methyl-pho...) Show SMILES CCCCCCCCCCCCCCN1CCC(O)(CC1)P(C)(O)=O Show InChI InChI=1S/C20H42NO3P/c1-3-4-5-6-7-8-9-10-11-12-13-14-17-21-18-15-20(22,16-19-21)25(2,23)24/h22H,3-19H2,1-2H3,(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [33P]-S1P binding to human Sphingosine 1-phosphate receptor 1 expressed on CHO cell membranes				Bioorg Med Chem Lett 14: 4861-6 (2004) Article DOI: 10.1016/j.bmcl.2004.07.049 BindingDB Entry DOI: 10.7270/Q2BK1D38
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 5 (Homo sapiens (Human))	BDBM50152321 ((4-Hydroxy-1-tetradecyl-piperidin-4-yl)-methyl-pho...) Show SMILES CCCCCCCCCCCCCCN1CCC(O)(CC1)P(C)(O)=O Show InChI InChI=1S/C20H42NO3P/c1-3-4-5-6-7-8-9-10-11-12-13-14-17-21-18-15-20(22,16-19-21)25(2,23)24/h22H,3-19H2,1-2H3,(H,23,24)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [33P]-S1P binding to human Sphingosine 1-phosphate receptor 5 expressed on CHO cell membranes				Bioorg Med Chem Lett 14: 4861-6 (2004) Article DOI: 10.1016/j.bmcl.2004.07.049 BindingDB Entry DOI: 10.7270/Q2BK1D38
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 4 (Homo sapiens (Human))	BDBM50152321 ((4-Hydroxy-1-tetradecyl-piperidin-4-yl)-methyl-pho...) Show SMILES CCCCCCCCCCCCCCN1CCC(O)(CC1)P(C)(O)=O Show InChI InChI=1S/C20H42NO3P/c1-3-4-5-6-7-8-9-10-11-12-13-14-17-21-18-15-20(22,16-19-21)25(2,23)24/h22H,3-19H2,1-2H3,(H,23,24)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [33P]-S1P binding to human Sphingosine 1-phosphate receptor 4 expressed on CHO cell membranes				Bioorg Med Chem Lett 14: 4861-6 (2004) Article DOI: 10.1016/j.bmcl.2004.07.049 BindingDB Entry DOI: 10.7270/Q2BK1D38
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human))	BDBM50152321 ((4-Hydroxy-1-tetradecyl-piperidin-4-yl)-methyl-pho...) Show SMILES CCCCCCCCCCCCCCN1CCC(O)(CC1)P(C)(O)=O Show InChI InChI=1S/C20H42NO3P/c1-3-4-5-6-7-8-9-10-11-12-13-14-17-21-18-15-20(22,16-19-21)25(2,23)24/h22H,3-19H2,1-2H3,(H,23,24)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [33P]-S1P binding to human Sphingosine 1-phosphate receptor 3 expressed on CHO cell membranes				Bioorg Med Chem Lett 14: 4861-6 (2004) Article DOI: 10.1016/j.bmcl.2004.07.049 BindingDB Entry DOI: 10.7270/Q2BK1D38
					More data for this Ligand-Target Pair