BDBM50152340 4-[6-Methoxy-7-(2-piperidin-1-yl-ethoxy)-quinazolin-4-yl]-piperazine-1-carbothioic acid 4-pyridin-4-yl-benzylamide::CHEMBL183929

SMILES: COc1cc2c(ncnc2cc1OCCN1CCCCC1)N1CCN(CC1)C(=S)NCc1ccc(cc1)-c1ccncc1

InChI Key: InChIKey=AKXNJHZVODKEML-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50152340   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50152340 (4-[6-Methoxy-7-(2-piperidin-1-yl-ethoxy)-quinazoli...) Show SMILES COc1cc2c(ncnc2cc1OCCN1CCCCC1)N1CCN(CC1)C(=S)NCc1ccc(cc1)-c1ccncc1 Show InChI InChI=1S/C33H39N7O2S/c1-41-30-21-28-29(22-31(30)42-20-19-38-13-3-2-4-14-38)36-24-37-32(28)39-15-17-40(18-16-39)33(43)35-23-25-5-7-26(8-6-25)27-9-11-34-12-10-27/h5-12,21-22,24H,2-4,13-20,23H2,1H3,(H,35,43)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.53E+3	n/a	n/a	n/a	n/a	n/a	n/a
and In Vivo Sciences Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of Platelet derived growth factor receptor beta autophosphorylation in MG-63 cells without plasma				Bioorg Med Chem Lett 14: 4867-72 (2004) Article DOI: 10.1016/j.bmcl.2004.07.041 BindingDB Entry DOI: 10.7270/Q2VM4BQN
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50152340 (4-[6-Methoxy-7-(2-piperidin-1-yl-ethoxy)-quinazoli...) Show SMILES COc1cc2c(ncnc2cc1OCCN1CCCCC1)N1CCN(CC1)C(=S)NCc1ccc(cc1)-c1ccncc1 Show InChI InChI=1S/C33H39N7O2S/c1-41-30-21-28-29(22-31(30)42-20-19-38-13-3-2-4-14-38)36-24-37-32(28)39-15-17-40(18-16-39)33(43)35-23-25-5-7-26(8-6-25)27-9-11-34-12-10-27/h5-12,21-22,24H,2-4,13-20,23H2,1H3,(H,35,43)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.04E+3	n/a	n/a	n/a	n/a	n/a	n/a
and In Vivo Sciences Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of Platelet derived growth factor receptor beta autophosphorylation in MG-63 cells with 45% human plasma				Bioorg Med Chem Lett 14: 4867-72 (2004) Article DOI: 10.1016/j.bmcl.2004.07.041 BindingDB Entry DOI: 10.7270/Q2VM4BQN
					More data for this Ligand-Target Pair